Background: In 2005, the US Congress allocated $612 million for a national Safe Routes to School (SRTS) program to encourage walking and bicycling to schools. We evaluated the effectiveness of a Safe Routes to School Program (SRTS) in controlling pedestrian injuries among school-age children. Methods: Bayesian changepoint analysis of quarterly counts of pedestrian injuries among 5 to 19-year- old children in New York City between 2001 and 2010 during school-travel hours in census tracts with and without SRTS. Overdispersed Poisson modeling for difference in differences following the changepoint. Results: In SRTS-intervention census tracts, a change point in the quarterly counts of injuries was identified in the second quarter of 2008, which...