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Impact of CYP2C9 genotype on pharmacokinetics: are all NSAIDs the same?

Oijen, M.G.H. van
Laheij, R.J.F.

Publication date

January 2007

DOI

10.1053/j.gastro.2007.10.019

ISSN

0016-5085

Citation count (estimate)

1

Abstract

Contains fulltext : 52918.pdf (publisher's version ) (Closed access

Extracted data

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Zhou, S
Zhou, Z
Huang, M

January 2009

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The influence of NSAIDs on coumarin sensitivity in patients with CYP2C9 polymorphism after total hip replacement surgery.

Beinema, M.J.
Jong, P.H. de
Salden, H.J.
Wijnen, M.H.W.A.
Meer, J.W.M. van der
Brouwers, J.R.B.J.

January 2007

Item does not contain fulltextOBJECTIVE: To determine the influence of NSAIDs on the international n...

The effect of genetic factors on the pharmacokinetics of drugs

Šlosárková, Petra

January 2009

The interindividual differences of activity of biotransformation enzymes play an important role in d...

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August 2016

Currently, genotyping of patients for polymorphic enzymes responsible for metabolic elimi-nation is ...

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Martin, JH
Begg, EJ
Kennedy, MA
Roberts, R
Barclay, ML

June 2001

Aims The aim of this study was to explore whether genetic variation of cytochrome P450 2C9 (CYP2C9) ...

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Rollason, Victoria
Samer, Caroline Flora
Daali, Youssef
Desmeules, Jules Alexandre

January 2014

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most frequently used drugs, either on prescri...

Clinical drugs undergoing polymorphic metabolism by human cytochrome P450 2C9 and the implication in drug development

He, S
Zhou, Z
Li, X
Zhou, S

January 2011

CYP2C9 metabolizes more than 100 clinically used drugs including phenytoin, S-warfarin, tolbutamide,...

Allele variants of the cytochrome P4502C9 genotype in white subjects from the Netherlands with serious gastroduodenal ulcers attributable to the use of NSAIDs

Vonkeman, H.E.
van de Laar, M.A.F.J.
Brouwers, J.R.B.J.
Vermes, I.

January 2006

Background: The most common serious adverse effects (AEs) associated with NSAID therapy are bleeding...

CYP2C9 Polymorphism and Use of Oral Nonsteroidal Anti-Inflammatory Drugs

Kathuria, Avani
Roosan, Moom
Sharma, Ajay

March 2021

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for management of inflammation and p...

No modification of the beneficial effect of NSAIDs on colorectal cancer by CYP2C9 genotype

Siemes, Claire
Eijgelsheim, Mark
Dieleman, Jeanne
van Schaik, Ron
Uitterlinden, André
Duijn, Cornelia
Hofman, Bert
Coebergh, Jan Willem
Stricker, Bruno
Visser, Loes

January 2009

Background: CYP2C9 enzymes are involved in non-steroidal anti-inflammatory drug (NSAID) metabolism. ...

PharmVar GeneFocus: CYP2C9

Sangkuhl, Katrin
Claudio‐Campos, Karla
Cavallari, Larisa H.
Agundez, Jose A.G.
Whirl‐Carrillo, Michelle
Duconge, Jorge
Del Tredici, Andria L.
Wadelius, Mia
Rodrigues Botton, Mariana
Woodahl, Erica L.
Scott, Stuart A.
Klein, Teri E.
Pratt, Victoria M.
Daly, Ann K.
Gaedigk, Andrea

September 2021

The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature for the pol...

Genetic variations in cytochrome P450 2C9 and 2C19: A review

Marjani, A.

January 2016

DNA polymorphisms have an important role in the genes encoding. A number of cytochrome P450 (CYP) en...

Allele variants of the cytochrome P450 2C9 Genotype in white subjects from The Netherlands with serious gastroduodenal ulcers attributable to the use of NSAIDs

Vonkeman, Harald Erwin
van de Laar, Mart A F J
van der Palen, Jacobus Adrianus Maria
Brouwers, Jacobus R.B.J.
Vermes, I.

January 2006

Background: The most common serious adverse effects (AEs) associated with NSAID therapy are bleeding...