Contains fulltext : 50745thebault.pdf (publisher's version ) (Closed access)One major clinical problem with prostate cancer is the cells' ability to survive and proliferate upon androgen withdrawal. Because Ca2+ is central to growth control, understanding the mechanisms of Ca2+ homeostasis involved in prostate cancer cell proliferation is imperative for new therapeutic strategies. Here, we show that agonist-mediated stimulation of alpha1-adrenergic receptors (alpha1-AR) promotes proliferation of the primary human prostate cancer epithelial (hPCE) cells by inducing store-independent Ca2+ entry and subsequent activation of nuclear factor of activated T cells (NFAT) transcription factor. Such an agonist-induced Ca2+ entry (AC...
ABSTRACT: Purpose: Calcium entry channels in the plasma membrane are thought to play a major role in...
International audienceAlthough the transient receptor potential melastatin 8 (TRPM8) cold receptor i...
Plasma membrane ion channels contribute to virtually all basic cellular processes, including such cr...
One major clinical problem with prostate cancer is the cells' ability to survive and proliferate upo...
One major clinical problem with prostate cancer is the cells' ability to survive and proliferate upo...
Contains fulltext : 47422thebault.pdf (publisher's version ) (Closed access)Prosta...
Contains fulltext : 53165thebault.pdf (publisher's version ) (Open Access)In recen...
Background: There is evidence that calcium (Ca2+) increases the proliferation of human advanced pros...
The transient receptor potential channel, subfamily V, member 6 (TRPV6), is strongly expressed in ad...
Contains fulltext : 48641thebault.pdf (publisher's version ) (Closed access)Neuroe...
International audienceThe transient receptor potential channel, subfamily V, member 6 (TRPV6), is st...
International audienceThe transient receptor potential channel, subfamily V, member 6 (TRPV6), is st...
The prostate gland is a rich source of alpha1-adrenergic receptors (alpha1-ARs). alpha1-AR antagonis...
To develop a new approach to the treatment of advanced, hor-mone-refractory prostate cancer, the sig...
Background: Androgen deprivation therapy (ADT) is the treatment of choice for metastatic prostate ca...
ABSTRACT: Purpose: Calcium entry channels in the plasma membrane are thought to play a major role in...
International audienceAlthough the transient receptor potential melastatin 8 (TRPM8) cold receptor i...
Plasma membrane ion channels contribute to virtually all basic cellular processes, including such cr...
One major clinical problem with prostate cancer is the cells' ability to survive and proliferate upo...
One major clinical problem with prostate cancer is the cells' ability to survive and proliferate upo...
Contains fulltext : 47422thebault.pdf (publisher's version ) (Closed access)Prosta...
Contains fulltext : 53165thebault.pdf (publisher's version ) (Open Access)In recen...
Background: There is evidence that calcium (Ca2+) increases the proliferation of human advanced pros...
The transient receptor potential channel, subfamily V, member 6 (TRPV6), is strongly expressed in ad...
Contains fulltext : 48641thebault.pdf (publisher's version ) (Closed access)Neuroe...
International audienceThe transient receptor potential channel, subfamily V, member 6 (TRPV6), is st...
International audienceThe transient receptor potential channel, subfamily V, member 6 (TRPV6), is st...
The prostate gland is a rich source of alpha1-adrenergic receptors (alpha1-ARs). alpha1-AR antagonis...
To develop a new approach to the treatment of advanced, hor-mone-refractory prostate cancer, the sig...
Background: Androgen deprivation therapy (ADT) is the treatment of choice for metastatic prostate ca...
ABSTRACT: Purpose: Calcium entry channels in the plasma membrane are thought to play a major role in...
International audienceAlthough the transient receptor potential melastatin 8 (TRPM8) cold receptor i...
Plasma membrane ion channels contribute to virtually all basic cellular processes, including such cr...