The environmental conditions may play a relevant role in the stability of rock slopes. In fact, weathering can contribute either to the reduction of strength of the material or to the increasing of internal stresses in the rock massif. This Ph.D. thesis deals with the effect of atmospheric thermal cycles in rocks, from both experimental and numerical point of view. This research is focused on the rock obtained from the cliff from La Roque Gageac, a small town located in the south-west of France, placed above a rock cliff that has a cavern at middle high. This village has been affected by several rock falls, which, based on instrumentation data, are linked to the in situ thermal variations. With the aim of isolating the effect of thermal cyc...