Treg in the Circulation of Celiac Disease Patients
- van Leeuwen Marieke A.
- du Pré M. Fleur
- van Wanrooij Roy L.
- de Ruiter Lilian F.
- Raatgeep H. (Rolien) C.
- Lindenbergh-Kortleve Dicky J.
- Mulder Chris J.
- de Ridder Lissy
- Escher Johanna C.
- Samsom Janneke N.
DOIAbstract
Treg in peripheral blood of CD patients. In particular, we compared pediatric CD, aiming to select for disease at onset, with adult CD.Cell surface markers, intracellular Foxp3 and Helios were determined by flow cytometry. Foxp3 expression was also detected by immunohistochemistry in duodenal tissue of CD patients. Treg frequencies were observed. Treg occur in a subset of adult patients on a gluten-free diet and in refractory CD patients
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