Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody

Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

Richard G. Conway
Eyassu Chernet
David C. De Rosa
Robert J. Benschop
Anne B. Need
Emily C. Collins
James S. Bean
J. Michael Kalbfleisch
Mark D. Rekhter

August 2016

Background: 18F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging of atheroscleros...

Vulnerable plaque and vulnerable blood: Two critical factors for spontaneous atherothrombosis in mouse models

Ouweneel, A.B.
Verwilligen, R.A.F.
Eck, M. van

March 2019

Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbi...

Molecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis

심지영

January 2015

BACKGROUND: Nonthrombotic platelet-endothelial interactions may contribute to atherosclerotic plaque...

Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody.

Timo Heidt
Friederike Deininger
Karlheinz Peter
Jürgen Goldschmidt
Annette Pethe
Christoph E Hagemeyer
Irene Neudorfer
Andreas Zirlik
Wolfgang A Weber
Christoph Bode
Philipp T Meyer
Martin Behe
Constantin von Zur Mühlen

BACKGROUND: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...

Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody

Radiolabeled Single-chain Antibody
Timo Heidt
See Profile
Friederike Braun
Christoph Eugen Hagemeyer
Andreas Zirlik
Timo Heidt
Friederike Deininger
Karlheinz Peter
Annette Pethe
Christoph E. Hagemeyer
Irene Neudorfer
Andreas Zirlik
Wolfgang A. Weber
Christoph Bode
Martin Behe
Constantin Von Zur Mühlen

January 2016

Background: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...

In Vivo Detection of Activated Platelets Allows Characterizing Rupture of Atherosclerotic Plaques with Molecular Magnetic Resonance Imaging in Mice

Dominik Von Elverfeldt
Constantin Von Zur Muhlen
Kristina Wiens
Irene Neudorfer
Andreas Zirlik
Mirko Meissner
Peg Tilly
Anne-laure Charles
Christoph Bode
Karlheinz Peter

August 2016

Background: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...

In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice.

Dominik von Elverfeldt
Constantin von zur Muhlen
Kristina Wiens
Irene Neudorfer
Andreas Zirlik
Mirko Meissner
Peg Tilly
Anne-Laure Charles
Christoph Bode
Karlheinz Peter
Jean-Etienne Fabre

BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...

Imaging thrombosis with (99m)Tc-labeled RAM.1-antibody in vivo

Ouadi, Ali
Bekaert, Virgile
Receveur, Nicolas
Thomas, Lionel
Lanza, François
Marchand, Patrice
Gachet, Christian
Mangin, Pierre Henri
Brasse, David
Laquerriere, Patrice

January 2018

Introduction: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus...

In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice

von Elverfeldt, D. (D)
von zur Muhlen, C. (C)
Wiens, K. (K)
Neudorfer, I. (I)
Zirlik, A. (A)
Meissner, M. (M)
Tilly, P. (Peggy)
Charles, A. (A) L. (L)
Bode, C. (C)
Peter, K. (K)
Fabre, J. (J) E. (E)

January 2012

BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...

Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.

von zur Muhlen, C
von Elverfeldt, D
Moeller, JA
Choudhury, RP
Paul, D
Hagemeyer, CE
Olschewski, M
Becker, A
Neudorfer, I
Bassler, N
Schwarz, M
Bode, C
Peter, K

July 2008

BACKGROUND: Platelets are the key to thrombus formation and play a role in the development of athero...

Nuclear medicine and biology

Ouadi, A. (Ali)
Bekaert, V. (Virgile)
Receveur, N. (Nicolas)
Thomas, L. (Lionel)
Lanza, F. (Francois)
Marchand, P. (Patrice)
Gachet, C. (Christian)
Mangin, P. (Pierre) H. (H)
Brasse, D. (David)
Laquerriere, P. (Patrice)

January 2018

INTRODUCTION: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus...

Imaging thrombosis with 99mTc-labeled RAM.1-antibody in vivo.

Ouadi, A. (Ali)
Bekaert, V. (Virgile)
Receveur, N. (Nicolas)
Thomas, L. (Lionel)
Lanza, F. (François)
Marchand, P. (Patrice)
Gachet, C. (Christian)
Mangin, P. (Pierre H)
Brasse, D. (David)
Laquerriere, P. (Patrice)

June 2018

Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ulti...

Immuno-PET Imaging of Atherosclerotic Plaques with [89 Zr]Zr-Anti-CD40 mAb—Proof of Concept

Poels, Kikkie
Schreurs, Maxime
Jansen, Matthijs
Vugts, Danielle J.
Seijkens, Tom T. P.
van Dongen, Guus A. M. S.
Lutgens, Esther
Beaino, Wissam

March 2022

Non-invasive imaging of atherosclerosis can help in the identification of vulnerable plaque lesions....

Platelet PI3Kγ contributes to activated platelet-induced overexpression of proinflammatory mediators in the carotid artery wall after partial ligation.

Cuiping Wang (401082)
Rong Jin (201093)
Anil Nanda (209096)
Jinchuan Yan (401079)
Guohong Li (207326)

June 2015

<p>(A, B) Representative images of ICAM-1 and VCAM-1 immunofluorescence staining for left common car...

Activated platelets: a potential new diagnostic and therapeutic target in preclinical experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis

Nair, Ashish Kumar Narayan

January 2016

Multiple sclerosis (MS) is a chronic autoimmune disease wherein the central nervous system (CNS) bec...

Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

Richard G. Conway
Eyassu Chernet
David C. De Rosa
Robert J. Benschop
Anne B. Need
Emily C. Collins
James S. Bean
J. Michael Kalbfleisch
Mark D. Rekhter

August 2016

Background: 18F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging of atheroscleros...

Vulnerable plaque and vulnerable blood: Two critical factors for spontaneous atherothrombosis in mouse models

Ouweneel, A.B.
Verwilligen, R.A.F.
Eck, M. van

March 2019

Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbi...

Molecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis

심지영

January 2015

BACKGROUND: Nonthrombotic platelet-endothelial interactions may contribute to atherosclerotic plaque...

Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody.

Timo Heidt
Friederike Deininger
Karlheinz Peter
Jürgen Goldschmidt
Annette Pethe
Christoph E Hagemeyer
Irene Neudorfer
Andreas Zirlik
Wolfgang A Weber
Christoph Bode
Philipp T Meyer
Martin Behe
Constantin von Zur Mühlen

BACKGROUND: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...

Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody

Radiolabeled Single-chain Antibody
Timo Heidt
See Profile
Friederike Braun
Christoph Eugen Hagemeyer
Andreas Zirlik
Timo Heidt
Friederike Deininger
Karlheinz Peter
Annette Pethe
Christoph E. Hagemeyer
Irene Neudorfer
Andreas Zirlik
Wolfgang A. Weber
Christoph Bode
Martin Behe
Constantin Von Zur Mühlen

January 2016

Background: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...

In Vivo Detection of Activated Platelets Allows Characterizing Rupture of Atherosclerotic Plaques with Molecular Magnetic Resonance Imaging in Mice

Dominik Von Elverfeldt
Constantin Von Zur Muhlen
Kristina Wiens
Irene Neudorfer
Andreas Zirlik
Mirko Meissner
Peg Tilly
Anne-laure Charles
Christoph Bode
Karlheinz Peter

August 2016

Background: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...

In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice.

Dominik von Elverfeldt
Constantin von zur Muhlen
Kristina Wiens
Irene Neudorfer
Andreas Zirlik
Mirko Meissner
Peg Tilly
Anne-Laure Charles
Christoph Bode
Karlheinz Peter
Jean-Etienne Fabre

BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...

Imaging thrombosis with (99m)Tc-labeled RAM.1-antibody in vivo

Ouadi, Ali
Bekaert, Virgile
Receveur, Nicolas
Thomas, Lionel
Lanza, François
Marchand, Patrice
Gachet, Christian
Mangin, Pierre Henri
Brasse, David
Laquerriere, Patrice

January 2018

Introduction: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus...

In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice

von Elverfeldt, D. (D)
von zur Muhlen, C. (C)
Wiens, K. (K)
Neudorfer, I. (I)
Zirlik, A. (A)
Meissner, M. (M)
Tilly, P. (Peggy)
Charles, A. (A) L. (L)
Bode, C. (C)
Peter, K. (K)
Fabre, J. (J) E. (E)

January 2012

BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...

Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.

von zur Muhlen, C
von Elverfeldt, D
Moeller, JA
Choudhury, RP
Paul, D
Hagemeyer, CE
Olschewski, M
Becker, A
Neudorfer, I
Bassler, N
Schwarz, M
Bode, C
Peter, K

July 2008

BACKGROUND: Platelets are the key to thrombus formation and play a role in the development of athero...

Nuclear medicine and biology

Ouadi, A. (Ali)
Bekaert, V. (Virgile)
Receveur, N. (Nicolas)
Thomas, L. (Lionel)
Lanza, F. (Francois)
Marchand, P. (Patrice)
Gachet, C. (Christian)
Mangin, P. (Pierre) H. (H)
Brasse, D. (David)
Laquerriere, P. (Patrice)

January 2018

INTRODUCTION: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus...

Imaging thrombosis with 99mTc-labeled RAM.1-antibody in vivo.

Ouadi, A. (Ali)
Bekaert, V. (Virgile)
Receveur, N. (Nicolas)
Thomas, L. (Lionel)
Lanza, F. (François)
Marchand, P. (Patrice)
Gachet, C. (Christian)
Mangin, P. (Pierre H)
Brasse, D. (David)
Laquerriere, P. (Patrice)

June 2018

Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ulti...

Immuno-PET Imaging of Atherosclerotic Plaques with [89 Zr]Zr-Anti-CD40 mAb—Proof of Concept

Poels, Kikkie
Schreurs, Maxime
Jansen, Matthijs
Vugts, Danielle J.
Seijkens, Tom T. P.
van Dongen, Guus A. M. S.
Lutgens, Esther
Beaino, Wissam

March 2022

Non-invasive imaging of atherosclerosis can help in the identification of vulnerable plaque lesions....

Platelet PI3Kγ contributes to activated platelet-induced overexpression of proinflammatory mediators in the carotid artery wall after partial ligation.

Cuiping Wang (401082)
Rong Jin (201093)
Anil Nanda (209096)
Jinchuan Yan (401079)
Guohong Li (207326)

June 2015

<p>(A, B) Representative images of ICAM-1 and VCAM-1 immunofluorescence staining for left common car...

Activated platelets: a potential new diagnostic and therapeutic target in preclinical experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis

Nair, Ashish Kumar Narayan

January 2016

Multiple sclerosis (MS) is a chronic autoimmune disease wherein the central nervous system (CNS) bec...

Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

Richard G. Conway
Eyassu Chernet
David C. De Rosa
Robert J. Benschop
Anne B. Need
Emily C. Collins
James S. Bean
J. Michael Kalbfleisch
Mark D. Rekhter

August 2016

Background: 18F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging of atheroscleros...

Vulnerable plaque and vulnerable blood: Two critical factors for spontaneous atherothrombosis in mouse models

Ouweneel, A.B.
Verwilligen, R.A.F.
Eck, M. van

March 2019

Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbi...

Molecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis

심지영

January 2015

BACKGROUND: Nonthrombotic platelet-endothelial interactions may contribute to atherosclerotic plaque...

Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody

Abstract

Extracted data

Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody

Abstract

Extracted data

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