Gas6 and the Receptor Tyrosine Kinase Axl in Clear Cell Renal Cell Carcinoma

The molecular biology of renal cell carcinoma (RCC) is complex and not fully understood. We have recently found that the expression of the receptor tyrosine kinase Axl in the RCC tumors independently correlates with survival of the patients..These results provide novel information regarding the complex function of the Gas6/Axl system in ccRCC