Gene Polymorphisms in Coal Workers' Pneumoconiosis in China: A Case-Control Study

and coal workers' pneumoconiosis (CWP) risk in a Chinese population.) were genotyped and analyzed in a case-control study of 556 CWP and 541 control subjects. = 0.023), and individuals with 11–12 risk alleles had a 47% higher risk of CWP than those with 0–8 risk alleles (OR = 1.47, 95% CI = 1.05–2.05). C-590T polymorphism is involved in the etiology of CWP and susceptibility to this disease. Larger studies are warranted to validate our findings