Isolation and Characterization of CvIV4: A Pain Inducing α- Scorpion Toxin
- Rowe Ashlee H.
- Xiao Yucheng
- Scales Joseph
- Linse Klaus D.
- Rowe Matthew P.
- Cummins Theodore R.
- Zakon Harold H.
DOIAbstract
channel isoforms.1.7 channels (D1586A and E1589Q, DIV S3–S4 linker) reduced but did not abolish the effects of CvIV4.1.7 have diverged in sequence, but the activity of these toxins is similar. Pain-inducing toxins may have evolved in a common ancestor. Alternatively, these toxins may be the product of convergent evolution
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