The Effect of Intermittent Antenatal Iron Supplementation on Maternal and Infant Outcomes in Rural Viet Nam: A Cluster Randomised Trial
- Hanieh Sarah
- Ha Tran T.
- Simpson Julie A.
- Casey Gerard J.
- Khuong Nguyen C.
- Thoang Dang D.
- Thuy Tran T.
- Pasricha Sant-Rayn
- Tran Thach D.
- Tuan Tran
- Dwyer Terence
- Fisher Jane
- Biggs Beverley-Ann
DOIAbstract
Anemia affects over 500 million women, and in pregnancy is associated with impaired maternal and infant outcomes. Intermittent antenatal iron supplementation is an attractive alternative to daily dosing; however, the impact of this strategy on infant outcomes remains unclear. We compared the effect of intermittent antenatal iron supplementation with daily iron supplementation on maternal and infant outcomes in rural Viet Nam.This cluster randomised trial was conducted in Ha Nam province, Viet Nam. 1,258 pregnant women (<16 wk gestation) in 104 communes were assigned to daily iron–folic acid (IFA), twice weekly IFA, or twice weekly multiple micronutrient (MMN) supplementation. Primary outcome was birth weight. Mean birth weight was 3,148 g (...
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