Seroprevalence of Pertussis in Senegal: A Prospective Study

). Seroepidemiology of pertussis has been widely described in industrialized countries, but rare are the studies referring to it in developing countries. by evaluating the IgG antibody (Ab) response against pertussis toxin (PT). A cohort of 410 children aged 1 to 9 from five villages in the Middle Senegal River Valley were followed-up for 18 months. During that period, five visits were made to assess the immunological status of the children., whereas in the other villages a pertussis endemic profile could be observed.Pertussis is endemic in Northern Senegal despite the introduction of vaccination. The circulation of the bacteria seems to differ between geographic locations and over time. A more complete understanding of the epidemiology of pertussis and its environmental determinants could provide information to adapt vaccination programs