We aimed to investigate whether an innovative growth factor-laden scaffold composed of acellular sciatic nerve (ASN) and brain-derived neurotrophic factor (BDNF) could promote axonal regeneration and functional recovery after spinal cord injury (SCI).Following complete transection at the thoracic level (T9), we immediately transplanted the grafts between the stumps of the severed spinal cords. We evaluated the functional recovery of the hindlimbs of the operated rats using the BBB locomotor rating scale system every week. Eight weeks after surgery, axonal regeneration was examined using the fluorogold (FG) retrograde tracing method. Electrophysiological analysis was carried out to evaluate the improvement in the neuronal circuits. Immunohis...
There have been many efforts to recover neuronal function from spinal cord injuries, but there are s...
Spinal cord injury often results in irreversible and permanent neurologic deficits below the lesion ...
© 2018 Masgutov, Masgutova, Mukhametova, Garanina, Arkhipova, Zakirova, Mukhamedshina, Margarita, Gi...
Objective: We aimed to investigate whether an innovative growth factor-laden scaffold composed of ac...
Purpose: The aversive nature of regenerative milieu is the main problem related to the failure of ne...
Purpose: The aversive nature of regenerative milieu is the main problem related to the failure of ne...
Program/Poster no. 724.7/F27We have previously shown that intra-neural injection of trophic factors ...
We previously showed that motor nerves are superior to sensory nerves in promoting axon regeneration...
Indiana University-Purdue University Indianapolis (IUPUI)After spinal cord injury (SCI), poor axonal...
Background: Recovery after injury to the peripheral nervous system is based on the pro-regenerative ...
The effects of neural stem cell (NSC) transplantation on repair in spinal cord injury are not ideal...
Chemically extracted acellular nerve allografts loaded with brain-derived neurotrophic factor-transf...
Spinal cord injury often results in irreversible and permanent neurologic deficits below the lesion ...
The most common type of spinal cord injury is the contusion of the spinal cord, which causes progres...
As part of the NIH "Facilities of Research Excellence-Spinal Cord Injury" project to support indepen...
There have been many efforts to recover neuronal function from spinal cord injuries, but there are s...
Spinal cord injury often results in irreversible and permanent neurologic deficits below the lesion ...
© 2018 Masgutov, Masgutova, Mukhametova, Garanina, Arkhipova, Zakirova, Mukhamedshina, Margarita, Gi...
Objective: We aimed to investigate whether an innovative growth factor-laden scaffold composed of ac...
Purpose: The aversive nature of regenerative milieu is the main problem related to the failure of ne...
Purpose: The aversive nature of regenerative milieu is the main problem related to the failure of ne...
Program/Poster no. 724.7/F27We have previously shown that intra-neural injection of trophic factors ...
We previously showed that motor nerves are superior to sensory nerves in promoting axon regeneration...
Indiana University-Purdue University Indianapolis (IUPUI)After spinal cord injury (SCI), poor axonal...
Background: Recovery after injury to the peripheral nervous system is based on the pro-regenerative ...
The effects of neural stem cell (NSC) transplantation on repair in spinal cord injury are not ideal...
Chemically extracted acellular nerve allografts loaded with brain-derived neurotrophic factor-transf...
Spinal cord injury often results in irreversible and permanent neurologic deficits below the lesion ...
The most common type of spinal cord injury is the contusion of the spinal cord, which causes progres...
As part of the NIH "Facilities of Research Excellence-Spinal Cord Injury" project to support indepen...
There have been many efforts to recover neuronal function from spinal cord injuries, but there are s...
Spinal cord injury often results in irreversible and permanent neurologic deficits below the lesion ...
© 2018 Masgutov, Masgutova, Mukhametova, Garanina, Arkhipova, Zakirova, Mukhamedshina, Margarita, Gi...