Both LFA-1 positive and -deficient T cell clones require the CD2/LFA-3 interaction for specific cytolytic activation

Kazuko Shibuya
Lewis L. Lanier
Joseph H. Phillips
Hans D. Ochs
Kenji Shimizu
Eiichi Nakayama
Hiromitsu Nakauchi
Akira Shibuya

October 2016

Whereas ligation of DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK and T cells...

Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.

Denning, SM
Dustin, ML
Springer, TA
Singer, KH
Haynes, BF

November 1988

Defining the cellular and molecular mechanisms of interaction of developing thymocytes with nonlymph...

Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells

Velde, A.A. te
Keizer, G.D.
Figdor, C.G.

January 1987

Contains fulltext : 27217___.PDF (publisher's version ) (Open Access

Distinct binding of T-lymphocytes to Icam-1, Icam-2 or Icam-3 upon activation of Lfa-1

Binnerts, M.E.
Kooyk, Y. van
Simmons, D.L.
Figdor, C.G.

January 1994

Contains fulltext : 27142___.PDF (publisher's version ) (Open Access

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

Kooyk, Y. van
Wiel-van Kemenade, P. van de
Weder, P.
Kuijpers, T.W.
Figdor, C.G.

January 1989

Contains fulltext : 27200.PDF (publisher's version ) (Open Access

Abnormal Cytolytic Activity of Lymphocyte Function-associated Antigen-1-deficient Human Cytolytic T Lymphocyte

Steven J. Mentzer
Barbara E. Bierer
Donald C. Anderson
Timothy A. Springer
Steven J. Burakoff

September 2016

The involvement of the lymphocyte function-associated antigen-1 (LFA-1) membrane molecule in cytolyt...

Role of LFA-1 and VLA-4 in the adhesion of cloned normal and LFA-1 (CD11/CD18)-deficient T cells to cultured endothelial cells: indication for a new adhesion pathway

Vennegoor, C.J.G.M.
Wiel-van Kemenade, E. van de
Huijbens, R.J.F.
Sanchez-Madrid, F.
Melief, C.J.M.
Figdor, C.G.

January 1992

Contains fulltext : 27182___.PDF (publisher's version ) (Open Access

Molecular mechanisms involved in T cell activation. I. Evidence for independent signal-transducing pathways in lymphokine production vs proliferation in cloned cytotoxic T lymphocytes

Harris, D. T.
Kozumbo, W. J.
Cerutti, P.
Cerottini, J. C.

January 1987

It is well-established that activated T cells proliferate in response to interleukin 2 (IL 2) and pr...

Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction

Pantaleo, G.
Zocchi, M. R.
Ferrini, S.
Poggi, A.
Tambussi, G.
Bottino, C.
Moretta, L.
Moretta, A.

July 1988

We have analyzed the transmembrane signaling operating in human cytolytic lymphocytes lacking surfac...

LFA-1 Contributes to Signal I of T-Cell Activation and to the Production of Th1 Cytokines

Varga, Georg
Nippe, Nadine
Balkow, Sandra
Peters, Thorsten
Wild, Martin K.
Seeliger, Stephan
Beissert, Stefan
Krummen, Mathias
Roth, Johannes
Sunderkötter, Cord
Grabbe, Stephan

April 2010

The β2 integrins are important for both transendothelial migration of leukocytes and T-cell activati...

T Cell Activation Pathways : B7, LFA-3, and ICAM-1 Shape Unique T Cell Profiles

Wingren, Anette Gjorloff
Parra, Eduardo
Varga, Mikael
Kalland, Terje
Sjogren, Hans Olov
Hedlund, Gunnar
Dohlsten, Mikael

January 2017

Two signals are required for induction of cell proliferation and cytokine production in resting T ce...

Clonal heterogeneity in the functional requirement for Lyt-2/3 molecules on cytolytic T lymphocytes: analysis by antibody blocking and selective trypsinization

MacDonald, H. R.
Glasebrook, A. L.
Cerottini, J. C.

December 1982

While it is well established that murine cytolytic T lymphocytes (CTL) express the Lyt-2/3 molecular...

Clonal analysis of cytolytic T lymphocyte-mediated lysis of target cells with inducible antigen expression: correlation between antigen density and requirement for Lyt-2/3 function

Shimonkevitz, R.
Luescher, B.
Cerottini, J. C.
MacDonald, H. R.

August 1985

The lysis by allospecific cytolytic T lymphocytes (CTL) of the BALB/c lymphoma ST-4.5, a cell line t...

Physical and Functional Association of LFA-1 with DNAM-1 Adhesion Molecule

Shibuya, Kazuko
Lanier, Lewis L
Phillips, Joseph H
Ochs, Hans D
Shimizu, Kenji
Nakayama, Eiichi
Nakauchi, Hiromitsu
Shibuya, Akira

November 1999

AbstractWhereas ligation of the DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK...

Activation of LFA-1 through a Ca2+-dependent epitope stimulates lymphocyte adhesion

Kooyk, Y. van
Weder, P.
Hogervorst, F.
Verhoeven, A.J.
Seventer, G. van
Velde, A.A. te
Borst, J.
Keizer, G.D.
Figdor, C.G.

January 1991

Contains fulltext : 27183.PDF (publisher's version ) (Open Access

Summary

Kazuko Shibuya
Lewis L. Lanier
Joseph H. Phillips
Hans D. Ochs
Kenji Shimizu
Eiichi Nakayama
Hiromitsu Nakauchi
Akira Shibuya

October 2016

Whereas ligation of DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK and T cells...

Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.

Denning, SM
Dustin, ML
Springer, TA
Singer, KH
Haynes, BF

November 1988

Defining the cellular and molecular mechanisms of interaction of developing thymocytes with nonlymph...

Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells

Velde, A.A. te
Keizer, G.D.
Figdor, C.G.

January 1987

Contains fulltext : 27217___.PDF (publisher's version ) (Open Access

Distinct binding of T-lymphocytes to Icam-1, Icam-2 or Icam-3 upon activation of Lfa-1

Binnerts, M.E.
Kooyk, Y. van
Simmons, D.L.
Figdor, C.G.

January 1994

Contains fulltext : 27142___.PDF (publisher's version ) (Open Access

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

Kooyk, Y. van
Wiel-van Kemenade, P. van de
Weder, P.
Kuijpers, T.W.
Figdor, C.G.

January 1989

Contains fulltext : 27200.PDF (publisher's version ) (Open Access

Abnormal Cytolytic Activity of Lymphocyte Function-associated Antigen-1-deficient Human Cytolytic T Lymphocyte

Steven J. Mentzer
Barbara E. Bierer
Donald C. Anderson
Timothy A. Springer
Steven J. Burakoff

September 2016

The involvement of the lymphocyte function-associated antigen-1 (LFA-1) membrane molecule in cytolyt...

Role of LFA-1 and VLA-4 in the adhesion of cloned normal and LFA-1 (CD11/CD18)-deficient T cells to cultured endothelial cells: indication for a new adhesion pathway

Vennegoor, C.J.G.M.
Wiel-van Kemenade, E. van de
Huijbens, R.J.F.
Sanchez-Madrid, F.
Melief, C.J.M.
Figdor, C.G.

January 1992

Contains fulltext : 27182___.PDF (publisher's version ) (Open Access

Molecular mechanisms involved in T cell activation. I. Evidence for independent signal-transducing pathways in lymphokine production vs proliferation in cloned cytotoxic T lymphocytes

Harris, D. T.
Kozumbo, W. J.
Cerutti, P.
Cerottini, J. C.

January 1987

It is well-established that activated T cells proliferate in response to interleukin 2 (IL 2) and pr...

Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction

Pantaleo, G.
Zocchi, M. R.
Ferrini, S.
Poggi, A.
Tambussi, G.
Bottino, C.
Moretta, L.
Moretta, A.

July 1988

We have analyzed the transmembrane signaling operating in human cytolytic lymphocytes lacking surfac...

LFA-1 Contributes to Signal I of T-Cell Activation and to the Production of Th1 Cytokines

Varga, Georg
Nippe, Nadine
Balkow, Sandra
Peters, Thorsten
Wild, Martin K.
Seeliger, Stephan
Beissert, Stefan
Krummen, Mathias
Roth, Johannes
Sunderkötter, Cord
Grabbe, Stephan

April 2010

The β2 integrins are important for both transendothelial migration of leukocytes and T-cell activati...

T Cell Activation Pathways : B7, LFA-3, and ICAM-1 Shape Unique T Cell Profiles

Wingren, Anette Gjorloff
Parra, Eduardo
Varga, Mikael
Kalland, Terje
Sjogren, Hans Olov
Hedlund, Gunnar
Dohlsten, Mikael

January 2017

Two signals are required for induction of cell proliferation and cytokine production in resting T ce...

Clonal heterogeneity in the functional requirement for Lyt-2/3 molecules on cytolytic T lymphocytes: analysis by antibody blocking and selective trypsinization

MacDonald, H. R.
Glasebrook, A. L.
Cerottini, J. C.

December 1982

While it is well established that murine cytolytic T lymphocytes (CTL) express the Lyt-2/3 molecular...

Clonal analysis of cytolytic T lymphocyte-mediated lysis of target cells with inducible antigen expression: correlation between antigen density and requirement for Lyt-2/3 function

Shimonkevitz, R.
Luescher, B.
Cerottini, J. C.
MacDonald, H. R.

August 1985

The lysis by allospecific cytolytic T lymphocytes (CTL) of the BALB/c lymphoma ST-4.5, a cell line t...

Physical and Functional Association of LFA-1 with DNAM-1 Adhesion Molecule

Shibuya, Kazuko
Lanier, Lewis L
Phillips, Joseph H
Ochs, Hans D
Shimizu, Kenji
Nakayama, Eiichi
Nakauchi, Hiromitsu
Shibuya, Akira

November 1999

AbstractWhereas ligation of the DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK...

Activation of LFA-1 through a Ca2+-dependent epitope stimulates lymphocyte adhesion

Kooyk, Y. van
Weder, P.
Hogervorst, F.
Verhoeven, A.J.
Seventer, G. van
Velde, A.A. te
Borst, J.
Keizer, G.D.
Figdor, C.G.

January 1991

Contains fulltext : 27183.PDF (publisher's version ) (Open Access

Summary

Kazuko Shibuya
Lewis L. Lanier
Joseph H. Phillips
Hans D. Ochs
Kenji Shimizu
Eiichi Nakayama
Hiromitsu Nakauchi
Akira Shibuya

October 2016

Whereas ligation of DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK and T cells...

Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.

Denning, SM
Dustin, ML
Springer, TA
Singer, KH
Haynes, BF

November 1988

Defining the cellular and molecular mechanisms of interaction of developing thymocytes with nonlymph...

Differential function of LFA-1 family molecules (CD11 and CD18) in adhesion of human monocytes to melanoma and endothelial cells

Velde, A.A. te
Keizer, G.D.
Figdor, C.G.

January 1987

Contains fulltext : 27217___.PDF (publisher's version ) (Open Access

Both LFA-1 positive and -deficient T cell clones require the CD2/LFA-3 interaction for specific cytolytic activation

Abstract

Extracted data

Both LFA-1 positive and -deficient T cell clones require the CD2/LFA-3 interaction for specific cytolytic activation

Abstract

Extracted data

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