as a Marker of Progression in Primary Non-Muscle Invasive Bladder Cancer

expression level and progression in non-muscle invasive bladder cancer (NMIBC). mRNA levels were examined by real-time reverse transcriptase polymerase chain reaction (RT-PCR) analysis of 193 tumor specimens from patients with primary NMIBC. Expression data were analyzed in terms of clinical and experimental parameters. Kaplan-Meier curves and multivariate Cox regression models, respectively, were used to determine progression-free survival and to identify independent predictive parameters of progression. mRNA expression levels are a significant risk factor for disease progression in patients with primary NMIBC (HR: 10.042, CI:2.699–37.360, p = 0.001). expression level represents a potentially useful marker for predicting progression in primary NMIBC patients