Increased Expression of Fatty-Acid and Calcium Metabolism Genes in Failing Human Heart
- García-Rúa Vanessa
- Otero Manuel Francisco
- Lear Pamela Virginia
- Rodríguez-Penas Diego
- Feijóo-Bandín Sandra
- Noguera-Moreno Teresa
- Calaza Manuel
- Álvarez-Barredo María
- Mosquera-Leal Ana
- Parrington John
- Brugada Josep
- Portolés Manuel
- Rivera Miguel
- González-Juanatey José Ramón
- Lago Francisca
DOIAbstract
)-handling in the human heart.RT-qPCR was used to quantify mRNA expression and immunoblotting to confirm protein expression in left-ventricular myocardium from patients with HF (n = 36) without diabetes mellitus of ischaemic (ICM, n = 16) or dilated (DCM, n = 20) cardiomyopathy aetiology, and non-diseased donors (CTL, n = 6).-handling genes expression. In ICM there were six correlations, all distinct from those found in CTL. In DCM there were also six (all also different from those found in CTL): three were common to and three distinct from ICM.-handling genes
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