Complement, a complex system of serum proteins, contributes to host defense through multiple mechanisms. In this issue of Cell Host & Microbe, Sorbara et al. (2018) discovered that cytosolic pathogens opsonized by complement are restricted by autophagy. This unexpected role for complement is important for cell-autonomous immunity in the intestinal mucosa
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is an essential, homeostatic process by which cells break down their own components. Perha...
Several bacterial pathogens are targeted by macroautophagy (referred to as autophagy hereafter), and...
Complement, a complex system of serum proteins, contributes to host defense through multiple mechani...
International audienceThe complement system is a major component of innate immunity that participate...
The complement system is a well-characterized cascade of extracellular serum proteins that is activa...
Autophagy is a conserved pathway that sequesters cytoplasmic material and delivers it to lysosomes f...
Autophagy provides a mechanism for cells to conserve nutrients, but was recently associated with imm...
Crohnâ s disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. Susceptib...
SummaryThe mammalian intestine is colonized with a diverse community of bacteria that perform many b...
Infections with bacteria form an increasing threat for human health. This is mainly due to the fact ...
International audienceIn order to survive inside the host cell, bacterial pathogens have evolved a v...
Autophagy can orchestrate innate immune responses to bacterial infection by targeting invading patho...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is a conserved cellular degradative pathway that is now established to be a vital part of ...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is an essential, homeostatic process by which cells break down their own components. Perha...
Several bacterial pathogens are targeted by macroautophagy (referred to as autophagy hereafter), and...
Complement, a complex system of serum proteins, contributes to host defense through multiple mechani...
International audienceThe complement system is a major component of innate immunity that participate...
The complement system is a well-characterized cascade of extracellular serum proteins that is activa...
Autophagy is a conserved pathway that sequesters cytoplasmic material and delivers it to lysosomes f...
Autophagy provides a mechanism for cells to conserve nutrients, but was recently associated with imm...
Crohnâ s disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. Susceptib...
SummaryThe mammalian intestine is colonized with a diverse community of bacteria that perform many b...
Infections with bacteria form an increasing threat for human health. This is mainly due to the fact ...
International audienceIn order to survive inside the host cell, bacterial pathogens have evolved a v...
Autophagy can orchestrate innate immune responses to bacterial infection by targeting invading patho...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is a conserved cellular degradative pathway that is now established to be a vital part of ...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is an essential, homeostatic process by which cells break down their own components. Perha...
Several bacterial pathogens are targeted by macroautophagy (referred to as autophagy hereafter), and...
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