Emergence of Coxsackie A6 hand-foot-and-mouth disease and comparative severity of Coxsackie B vs. echovirus infections, 2014-2016, UK.

Enterovirus (EV) infections (n=102) in paediatric and adult patients, presenting with hand-foot-and-mouth disease (HFMD), suspected sepsis or viral meningitis during Jan 2014 to Dec 2016 were characterised. Coxsackie A6 was the predominant EV type in HFMD, Coxsackie B viruses caused more severe infections than echoviruses, based on laboratory parameter derangement. Single cases of EVD68 and EV71 from respiratory and skin samples, respectively, were identified, albeit with no neurological complications in either case