The enteric pathogens enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli employ a type 3 secretion system (T3SS) to manipulate the host inflammatory response during infection. Previously, it has been reported that EPEC, in a T3SS-dependent manner, induces an early proinflammatory response through activation of NF-κB via extracellular signal-regulated kinases 1 and 2 (ERK1/2) and protein kinase Cζ (PKCζ). However, the activation of NF-κB during infection has not yet been attributed to an effector. At later time points postinfection, NF-κB signaling is inhibited through the translocation of multiple effectors, including NleE and NleC. Here we report that the highly conserved non-LEE (locus of enterocyte effacement)-encoded...
The complex host-pathogen interplay involves the recognition of the pathogen by the host's innate im...
© 2016 Dr. Cristina GioghaEnteropathogenic Escherichia coli (EPEC) is a common cause of diarrhoea in...
Enteropathogenic E. coli (EPEC) is a diarrheagenic human pathogen. The hallmark of EPEC infection is...
The enteric pathogens enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli employ ...
Many bacterial pathogens utilize a type III secretion system (T3SS) to inject virulence effector pro...
© 2013 Dr. Jaclyn PearsonEnteropathogenic Escherichia coli (EPEC) is an extracellular gastrointestin...
The NF-kB signaling pathway is central to the innate and adaptive immune responses. Upon their detec...
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC, respectively) are attaching ...
The complex host-pathogen interplay involves the recognition of the pathogen by the host’s innate im...
Enteropathogenic Escherichia coli (EPEC) disease depends on the transfer of effector proteins into e...
Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins i...
ABSTRACT Translocation of effector proteins via a type III secretion system (T3SS) is a widespread i...
ABSTRACT Translocation of effector proteins via a type III secretion system (T3SS) is a widespread i...
© 2019 Georgina Lauren PollockDuring infection the gastrointestinal pathogen enteropathogenic Escher...
Translocation of effector proteins via a type III secretion system (T3SS) is a widespread infection ...
The complex host-pathogen interplay involves the recognition of the pathogen by the host's innate im...
© 2016 Dr. Cristina GioghaEnteropathogenic Escherichia coli (EPEC) is a common cause of diarrhoea in...
Enteropathogenic E. coli (EPEC) is a diarrheagenic human pathogen. The hallmark of EPEC infection is...
The enteric pathogens enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli employ ...
Many bacterial pathogens utilize a type III secretion system (T3SS) to inject virulence effector pro...
© 2013 Dr. Jaclyn PearsonEnteropathogenic Escherichia coli (EPEC) is an extracellular gastrointestin...
The NF-kB signaling pathway is central to the innate and adaptive immune responses. Upon their detec...
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC, respectively) are attaching ...
The complex host-pathogen interplay involves the recognition of the pathogen by the host’s innate im...
Enteropathogenic Escherichia coli (EPEC) disease depends on the transfer of effector proteins into e...
Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins i...
ABSTRACT Translocation of effector proteins via a type III secretion system (T3SS) is a widespread i...
ABSTRACT Translocation of effector proteins via a type III secretion system (T3SS) is a widespread i...
© 2019 Georgina Lauren PollockDuring infection the gastrointestinal pathogen enteropathogenic Escher...
Translocation of effector proteins via a type III secretion system (T3SS) is a widespread infection ...
The complex host-pathogen interplay involves the recognition of the pathogen by the host's innate im...
© 2016 Dr. Cristina GioghaEnteropathogenic Escherichia coli (EPEC) is a common cause of diarrhoea in...
Enteropathogenic E. coli (EPEC) is a diarrheagenic human pathogen. The hallmark of EPEC infection is...