BDNF-based therapeutic approach in schizophrenia and depression?

Decreased BDNF expression and function in particular and neurotropic factors in general seem to play a critical role in the pathogenesis of certain psychiatric disease as schizophrenia and depression, apparently due to their important role in regulating the survival development and regeneration of neurons.serum BDNF may provide a useful tool for the evaluation of cognitive enhancement methods in schizophrenia as well as signs concerning the mechanisms through which cognitive enhancement produces functional benefit, but the current knowledge is not sufficient to use BDNF as a marker for antipsychotic drug therapy effectiveness.egységes, osztatlanáltalános orvosangolOrvosbiológia-farmakológi