Target Therapy of Non-Hodgkin Lymphoma

Lymphoma could be divided into various types according to WHO classification or other classical ways. First I noted the types, diagnosis, and important prognostic factors of lymphoma. Before starting the discussion of the NHL treatment, B cell receptor signaling pathway and role of CD20 will be mentioned, which are essential mechanisms for the development of lymphoma treatment. In the chapter of NHL target therapy, I focused on the recent standard or trend treatments, which are anti-CD20 monoclonal antibody therapy such as rituximab, antibody-drug conjugated therapy, radiolabeled antibody therapy, and signal transduction inhibitors. I collected the data of clinical trials for each therapy and analyzed the efficacy and prognosis after the therapies.egységes, osztatlanáltalános orvosango