Ocular manifestations in albinism

Albinism is a hereditary condition characterized by hypopigmentation in the skin, eye and hair due to enzymatic defect or lack of enzymes in the melanin synthesis pathway and affects 1 in 17,000 people worldwide. Ocular manifestation such as photophobia, abnormal decussation of the optic nerve, nystagmus, strabismus, foveal hypoplasia, iris trans-illumination, decrease in visual acuity, refractory errors and astigmatism are classically seen in patients with albinism. In rare situations other ocular manifestation such as keratoconus can be seen with albinism.egységes, osztatlanáltalános orvosango