Step-Controlled Povarov-Type Reaction with 1,2-Dihydroquinolines as Precursors of Dienophiles: Direct Synthesis of Spirocyclic Bi-tetrahydroquinolines and Functionalized 1,2-Dihydroquinolines
- Ren, XW
- Li, GX
- Huang, J
- Wang, WD
- Zhang, YP
- Xing, GM
- Gao, CY
- Zhao, G
- Zhao, JZ
- Tang, Z
- Zhao, JZ (reprint author), Shanxi Agr Univ Taigu, Coll Art & Sci, Jinzhong 030800, Shanxi, Peoples R China.
- Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China.
Publication date
January 2017
DOI Publisher
American Chemical Society (ACS) ISSN
1523-7060 Citation count (estimate)
5Abstract
A novel Povarov-type reaction for straightforward synthesis of novel spiro bi-tetrahydroquinolines with readily available 1,2-DHQs (1,2-dihydroquinolines) and aromatic imines was developed. The reaction could be selectively stopped at the first stage under a Bronsted acid catalyst to afford the corresponding functionalized 1,2-DHQs conveniently
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