Unbalanced translocations generating trisomy of 1q are common in Wilms tumor (WT). We present eight unbalanced 1q translocations from seven tumors and a review of the literature. An unbalanced translocation that results in a der(16)t(1q;16q) chromosome represents more than half of the published +1q generating translocations in WT. This translocation is also common to many other tumor types. Four of the tumors presented here contained this chromosome and,in two cases, it was the primary acquired cytogenetic abnormality within the tumor. The other four translocations involved 9q31, 9q34, 17p1?, and 21p11 as the partner to 1q. The chromosome 17 and 21 translocations occurred within the same tumor as apparently independent events. In contrast w...
International audienceRecurrent chromosome translocations in nonhematological tumors are restricted ...
Chromosome 7p alterations have been implicated in the development of Wilms' tumour (WT) by previous ...
The present report describes the karyotypic findings in cells from a Wilms' tumor. The most consiste...
Unbalanced translocations generating trisomy of 1q are common in Wilms tumor (WT). We present eight ...
An extra copy of 1q usually originates from the translocated unbalanced derivative chromosome, isoch...
Cytogenetic analysis of predisposition syndromes has played a critical role in the elucidation of th...
Wilms tumor (WT) is characterized by a nonrandom pattern of chromosome aberrations, but the clinical...
Loss of heterozygosity studies have been used to identify chromosomal regions which are frequently d...
In 26 consecutive patients operated for Wilms' tumour samples from the tumour were genetically analy...
Sporadic childhood tumors associated with Beckwith-Wiedemann syndrome (BWS) all show abnormalities o...
Many solid tumors exhibit characteristic gene fusions, which are reflected by balanced translocation...
We report two cases of hematological malignancies, comprising a case of myelodysplastic syndrome (MD...
Wilms tumor (WT) has been a model to study kidney embryogenesis and tumorigenesis and, although asso...
Unbalanced 1q rearrangements are widely reported in myeloid and lymphoid malignancies. Among unbalan...
Wilms\u27 tumor (WT) is a childhood embryonic tumor of the kidney. In some cases, WT has been associ...
International audienceRecurrent chromosome translocations in nonhematological tumors are restricted ...
Chromosome 7p alterations have been implicated in the development of Wilms' tumour (WT) by previous ...
The present report describes the karyotypic findings in cells from a Wilms' tumor. The most consiste...
Unbalanced translocations generating trisomy of 1q are common in Wilms tumor (WT). We present eight ...
An extra copy of 1q usually originates from the translocated unbalanced derivative chromosome, isoch...
Cytogenetic analysis of predisposition syndromes has played a critical role in the elucidation of th...
Wilms tumor (WT) is characterized by a nonrandom pattern of chromosome aberrations, but the clinical...
Loss of heterozygosity studies have been used to identify chromosomal regions which are frequently d...
In 26 consecutive patients operated for Wilms' tumour samples from the tumour were genetically analy...
Sporadic childhood tumors associated with Beckwith-Wiedemann syndrome (BWS) all show abnormalities o...
Many solid tumors exhibit characteristic gene fusions, which are reflected by balanced translocation...
We report two cases of hematological malignancies, comprising a case of myelodysplastic syndrome (MD...
Wilms tumor (WT) has been a model to study kidney embryogenesis and tumorigenesis and, although asso...
Unbalanced 1q rearrangements are widely reported in myeloid and lymphoid malignancies. Among unbalan...
Wilms\u27 tumor (WT) is a childhood embryonic tumor of the kidney. In some cases, WT has been associ...
International audienceRecurrent chromosome translocations in nonhematological tumors are restricted ...
Chromosome 7p alterations have been implicated in the development of Wilms' tumour (WT) by previous ...
The present report describes the karyotypic findings in cells from a Wilms' tumor. The most consiste...