Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol-dependent functions such as cognition, cardiovascular function, and pain processing. Three common haplotypes of the human COMT gene, divergent in two synonymous and one nonsynonymous (val158met) position, designated as low (LPS), average (APS), and high pain sensitive (HPS), are associated with experimental pain sensitivity and risk of developing chronic musculoskeletal pain conditions. APS and HPS haplotypes produce significant functional effects, coding for 3- and 20-fold reductions in COMT enzymatic activity, respectively. In the present study, we investigated whether additional minor single nucleotide polymorphisms (SNPs), accruing in 1 ...
Xiang X, Jiang Y, Ni Y, Fan M, Shen F, Wang X, Han J, Cui C. Catechol-O-methyltransferase polymorphi...
Catechol O-methyltransferase (COMT) plays an Important role in the metabolism of catecholamlnes, cat...
Background Treatment outcome of low back pain (LBP) is associated with inter-individ...
Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol...
Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol...
Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol...
Background: Genetic variation in the catechol-O-methyltransferase (COMT) gene is associated with sen...
Copyright © 2006 International Association for the Study of Pain Published by Elsevier B.VVariations...
Catechol-O-methyltransferase, encoded by COMT gene, is the primary enzyme that metabolizes catechola...
Catechol-O-methyltransferase (COMT) metabolizes catecholaminergic neurotransmitters. Numerous studie...
Objectives The aim of this study was to investigate the association between the catechol-O-methyltra...
Catechol-O-methyltransferase (COMT) metabolizes catecholaminergic neurotransmitters. Numerous studie...
Abnormalities in the enzymatic activity of catechol-O-methyltransferase (COMT) contribute to chronic...
Abstract Background The Catechol-O-methyltransferase (COMT) gene contains a functional polymorphism,...
The enzyme catechol-O-methyltransferase (COMT) metabolizes catecholamine neurotransmitters involved ...
Xiang X, Jiang Y, Ni Y, Fan M, Shen F, Wang X, Han J, Cui C. Catechol-O-methyltransferase polymorphi...
Catechol O-methyltransferase (COMT) plays an Important role in the metabolism of catecholamlnes, cat...
Background Treatment outcome of low back pain (LBP) is associated with inter-individ...
Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol...
Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol...
Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol...
Background: Genetic variation in the catechol-O-methyltransferase (COMT) gene is associated with sen...
Copyright © 2006 International Association for the Study of Pain Published by Elsevier B.VVariations...
Catechol-O-methyltransferase, encoded by COMT gene, is the primary enzyme that metabolizes catechola...
Catechol-O-methyltransferase (COMT) metabolizes catecholaminergic neurotransmitters. Numerous studie...
Objectives The aim of this study was to investigate the association between the catechol-O-methyltra...
Catechol-O-methyltransferase (COMT) metabolizes catecholaminergic neurotransmitters. Numerous studie...
Abnormalities in the enzymatic activity of catechol-O-methyltransferase (COMT) contribute to chronic...
Abstract Background The Catechol-O-methyltransferase (COMT) gene contains a functional polymorphism,...
The enzyme catechol-O-methyltransferase (COMT) metabolizes catecholamine neurotransmitters involved ...
Xiang X, Jiang Y, Ni Y, Fan M, Shen F, Wang X, Han J, Cui C. Catechol-O-methyltransferase polymorphi...
Catechol O-methyltransferase (COMT) plays an Important role in the metabolism of catecholamlnes, cat...
Background Treatment outcome of low back pain (LBP) is associated with inter-individ...