Neck circumference is similarly predictng for impairment of glucose tolerance as classic anthropometric parameters among healthy and obese children and adolescents

Abstract Background: The objective of the study was to investigate the association of neck circumference (NC) to parameters of glucose homeostasis compared to classical anthropo- metric parameters of lean and obese children. Methods: Three dimensional (3D)-body scanning quan- tified anthropometric (height, weight, NC, hip/waist circumference, BMI) and metabolic parameters (fasting plasma glucose [FPG], insulin, HbA1c, oGTT, HOMA-IR) were determined cross-sectionally in 1542 participants (5–18 years). the strongest association to glucose metabolism para- meters was found for waist circumference (WC), except for FPG and 2h-postload glucose. In multiple linear regres- sion analyses, NC provided additional benefit beyond classical anthropometric indices to describe impairment of glucose homeostasis. Conclusions: We suggest that NC is comparable or addi- tive to established anthropometric parameters but might not be superior to them. However NC is simple to measure, reproducible and may be considered in clinical practice as an additional measurement tool.:Inhalt I Abkürzungsverzeichnis 1. Einführung in die Thematik 1.1. Einleitung und Definition 1.2. Zielsetzung der Arbeit 1.3. wissenschaftlicher Hintergrund 1.4. LIFE Child 2. Publikation Zusammenfassung der Arbeit Literaturverzeichnis Darstellung wissenschaftlicher Beitrag Erklärung über die eigenständige Abfassung der Arbeit Danksagun