The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment recovery from neurological disorders. To test this hypothesis, we conceived a brain-controlled neuromodulation therapy that combines the technical and practical features necessary to be deployed daily during gait rehabilitation. Rats received a severe spinal cord contusion that led to leg paralysis. We engineered a proportional brain-spine interface whereby cortical ensemble activity constantly determines the amplitude of spinal cord stimulation protocols promoting leg flexion during swing. After minimal calibration time and without prior training, this neural bypass enables paralyzed rats to walk overground and adjust foot clearance in order ...
Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of n...
A spinal cord injury usually spares some components of the locomotor circuitry. Deep brain stimulati...
Thesis (Ph.D.)--University of Washington, 2020Spinal cord injury (SCI) results in permanent neurolog...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in ani...
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in ani...
Traumatic SCIs have long-term health, economic and social consequences, stressing the urgency to dev...
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in ani...
© 2017, © The Author(s) 2017. Significant advancements in spinal epidural stimulation (ES) strategie...
Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of n...
A spinal cord injury usually spares some components of the locomotor circuitry. Deep brain stimulati...
Thesis (Ph.D.)--University of Washington, 2020Spinal cord injury (SCI) results in permanent neurolog...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment r...
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in ani...
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in ani...
Traumatic SCIs have long-term health, economic and social consequences, stressing the urgency to dev...
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in ani...
© 2017, © The Author(s) 2017. Significant advancements in spinal epidural stimulation (ES) strategie...
Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of n...
A spinal cord injury usually spares some components of the locomotor circuitry. Deep brain stimulati...
Thesis (Ph.D.)--University of Washington, 2020Spinal cord injury (SCI) results in permanent neurolog...