Reference environment for the manuscript ['Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca 2+ Release Patterns in Cardiomyocytes'](http://dx.doi.org/10.1371/journal.pcbi.1004417)

<p><strong>Overview</strong></p> <p><br> This is the reference environment for the manuscript ['Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca 2+ Release Patterns in Cardiomyocytes'](http://dx.doi.org/10.1371/journal.pcbi.1004417). It executes code to reproduce specific results described in the manuscript. You can find more information about this research at the [project page here](http://github.com/vraj004/RyR-simulator). </p> <p>To find other versions of this reference environment, see Other Links below. To learn more about reference environments, [see the detailed description here](http://uomsystemsbiology.github.io/reference-environments/). </p> <p><strong>Instructions for use</strong></p> <p>This version of the reference environment is a live image as a bootable read-only ISO. To use it:</p> <p>- Install a virtualization tool like [VirtualBox](https://www.virtualbox.org/), then<br> - Create a new virtual machine in the virtualization tool with a virtual CD/DVD-ROM drive<br> - Mount the ISO in the drive<br> - Boot the machine. </p> <p>This will start a virtual machine with scripts to run which reproduce results described in the manuscript. </p> <p>### Other links</p> <p>[Manuscript link](http://dx.doi.org/10.1371/journal.pcbi.1004417)</p> <p>[Project page link](http://github.com/vraj004/RyR-simulator)</p> <p>[Bootable ISO](http://dx.doi.org/10.5281/zenodo.32916)</p> <p>[Vagrant-managed virtual machine](http://github.com/uomsystemsbiology/ryr_simulator_reference_environment)</p> <p>