Parasitological outcome of TcTASV-C vaccinated mice challenged with a virulent <i>T</i>. <i>cruzi</i> strain.

<p>Groups of mice (n = 5) were immunized with TcTASV-C or vehicle (Control) and challenged with <i>T</i>. <i>cruzi</i> trypomastigotes of the RA strain (TcVI) 15 days after the last dose. Animals were followed up for parasitemia and survival. Parasitemia of individual mice at 9 (<b>A</b>) and 12 (<b>B</b>) days post-infection. (<b>C)</b> Parasitemia during the course of infection in TcTASV-C vaccinated and Control groups (*p<0.05 and ***p<0.005 vs control; Mann-Whitney test). (<b>D)</b> Survival curve of challenged TcTASV-C vaccinated and Control groups (**p<0.05 vs Control group; Log-Rank test).