Transfer of DCs obtained from OVA-treated mice reduces histopathological damages in the large intestine caused by TNBS-induced colitis.

<p>BALB/c mice were exposed to the treatments described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0196994#pone.0196994.g001" target="_blank">Fig 1</a> and euthanized 5 days after induction of colitis. Distal portions of the large gut were collected and fixed in paraffin for histological processing. Panels: Ethanol, TNBS, nDC+TNBS, and tDC+TNBS represent sections obtained from mice treated with ethanol, TNBS, nDC, and TNBS or tDC and TNBS, respectively. Histological sections of 5μm were stained with hematoxylin and eosin and examined using light microscopy (200X).M: Tunica Mucosa, MF: mucosal folds, LI: lymphocytic infiltrate, TM: Tunica Muscularis, SM: Tunica Submucosa, *: Mucosal crypts, and #: Detached mucosal tissue debris.