Figure S2. Low power views of G85R-SOD1:YFP pathology in the spinal cord of bigenic JNPL3-G85R-SOD1:YFP mice (a). The box marks the position of the image shown in Fig. 1d of the main text. Low power view of fluorescence in mice expressing G85R-SOD1:YFP alone (c). Images shows midsagittal brain section (b). Nuclei were stained with DAPI (blue). The left and right arrows are drawn to magnified regions that are shown in the top left and top right of (b), respectively. Images shown are representative of 8 JNPL3-G85R-SOD1:YFP mice and 3 G85R-SOD1:YFP mice. (TIF 8095Â kb
Behavioral analyses. Figure S1. Corner test. Figure S2. Open field test. Figure S3 Rotarod test. Fig...
Co-localization of α-synuclein and SOD1 in wt mouse brain. Representative images of C57Bl/6 wt mouse...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Figure S5. Localization of phosphotau immunoreactivity versus G85R-SOD1:YFP pathology in bigenic JNP...
Figure S3. Primary pathology burden in the JNPL3 spinal cord relative to those crossed to G85R-SOD1:...
Figure S8. Primary pathology burden in the M83 transgenic mouse spinal cord relative to M83/G85R-SOD...
Figure S11. G85R-SOD1:YFP expression in spinal cord is 2-fold higher than forebrain in G85R-SOD1:YFP...
Figure S7. Quantification of G85R-SOD1:YFP levels between G85R-SOD1:YFP and rTg4510/G85R-SOD1:YFP mi...
Figure S6. Primary pathology burden in the rTg4510 transgenic mouse cortex relative to those crossed...
Figure S4. Solubility of SOD1 in JNPL3/G85R-SOD1:YFP mice. For these immunoblots, we used a previous...
Figure S12. Hypothetical mechanism of differential effects of tauopathy versus synucleinopathy on G8...
Figure S2. Whole transverse sectional images of the lumbar spinal cord in Figs. 2, 3 and 4. a Whole ...
Figure S10. Solubility of αSyn and SOD1 in M83/G85R-SOD1:YFP mice. No changes in soluble versus NP40...
Figure S2. Additional distribution maps αS inclusion pathology in P0 injected M83+/− mice. αS pathol...
Table S1. RNAseq expression data for SOD1 in mouse and human tauopathies. Transcriptomic data from s...
Behavioral analyses. Figure S1. Corner test. Figure S2. Open field test. Figure S3 Rotarod test. Fig...
Co-localization of α-synuclein and SOD1 in wt mouse brain. Representative images of C57Bl/6 wt mouse...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Figure S5. Localization of phosphotau immunoreactivity versus G85R-SOD1:YFP pathology in bigenic JNP...
Figure S3. Primary pathology burden in the JNPL3 spinal cord relative to those crossed to G85R-SOD1:...
Figure S8. Primary pathology burden in the M83 transgenic mouse spinal cord relative to M83/G85R-SOD...
Figure S11. G85R-SOD1:YFP expression in spinal cord is 2-fold higher than forebrain in G85R-SOD1:YFP...
Figure S7. Quantification of G85R-SOD1:YFP levels between G85R-SOD1:YFP and rTg4510/G85R-SOD1:YFP mi...
Figure S6. Primary pathology burden in the rTg4510 transgenic mouse cortex relative to those crossed...
Figure S4. Solubility of SOD1 in JNPL3/G85R-SOD1:YFP mice. For these immunoblots, we used a previous...
Figure S12. Hypothetical mechanism of differential effects of tauopathy versus synucleinopathy on G8...
Figure S2. Whole transverse sectional images of the lumbar spinal cord in Figs. 2, 3 and 4. a Whole ...
Figure S10. Solubility of αSyn and SOD1 in M83/G85R-SOD1:YFP mice. No changes in soluble versus NP40...
Figure S2. Additional distribution maps αS inclusion pathology in P0 injected M83+/− mice. αS pathol...
Table S1. RNAseq expression data for SOD1 in mouse and human tauopathies. Transcriptomic data from s...
Behavioral analyses. Figure S1. Corner test. Figure S2. Open field test. Figure S3 Rotarod test. Fig...
Co-localization of α-synuclein and SOD1 in wt mouse brain. Representative images of C57Bl/6 wt mouse...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...