Enrichment of non-polymorphic sites with respect to stability evaluated in different structures.

<p>The p-values of enrichment analysis (column 3, also see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006188#pcbi.1006188.g003" target="_blank">Fig 3B</a>) of non-polymorphic residues among sites contributing most to protein stability using different pdb structures (column 2) of MHC-I alleles (column 1) is shown below. For each pdb structure, we merged the peptide and the MHC-I allele on the same chain and ran AlaScan to measure the stability scores.