Comparison of cfDNA CNVs and tumor tissue CNVs.

<p>A) Distribution of direct correlation between CNVs detected via cfDNA samples and CNVs identified in parent tumor tissue (Red); darker color represents higher stage (1–4). Distribution of highest correlation between CNVs detected via a cfDNA sample when compared to all tumor tissue samples (Green); darker color represents higher stage (1–4). B) Heatmap of potential CNVs detected via cfDNA sequencing along with CNVs identified in parent tumor tissue scaled separately. A value of 1 represents a normal diploid segment, values less than one are potential deletions, and values higher than one are potential amplifications.