Figure S1. Protein activity suppressed by inhibitors. Western blot quantification and short time point for phospho-ERK western blot. a) Quantification of western blot represented in Figure 2a showing protein level changes in BT549 or MDA MB 468 cells after 6 h treatment with indicated inhibitors. Quantification is relative to vehicle control lanes. b) Western blot showing decrease in phosphorylated ERK1/2 upon 30-min exposure to IKKε inhibitor, and accompanying graph for quantitation of phospho-ERK, as normalized to GAPDH, and relative to expression in untreated MDA468. (PPTX 429 kb
Figure S1. RTK expression and ERBB2-targeting antibody response in breast cancer cell lines. Figure ...
Figure S1. The PI3K/AKT pathway significantly contributes to the ligand-driven HER2 signaling activi...
Figure S1. Gating strategy for CDCP1 flow cytometric analysis. Flow cytometric analysis of MDA-MB-23...
Figure S4. IKKε and p52 or MEK supports viability in LA conditions in at least two TNBC lines. Growt...
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...
Table S1. IC50 values for selected inhibitors in breast cancer lines. IC50 values obtained in the cu...
Figure S3. IKKε inhibits activity of p52. qRT-PCR and ChIP-PCR results for MDA MB 231 cell line and ...
Figure S2. The MEK inhibitor PD98059 and the PI3K inhibitor Wortmannin prevent respectively the acti...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...
Figure S2. Knockdown of IKKε leads to increased expression of non-canonical NF-kB proteins in at lea...
Silencing SHP2 expression in the MDA-MB-231 (a) and MDA-MB-468 (b) cells drastically reduced EGFR pr...
Figure S1. miR-140-3p-1 modestly inhibits proliferation of breast preneoplastic cells. (A) Immunoflu...
Inhibition of NF-κB p65 affects FOXC1 protein levels. MDA-MB-468 cells were serum-starved overnight ...
FC-IBC02 cell proliferation assays: estimated time trends in response to different CEP-37440 concent...
Figure S1. RTK expression and ERBB2-targeting antibody response in breast cancer cell lines. Figure ...
Figure S1. The PI3K/AKT pathway significantly contributes to the ligand-driven HER2 signaling activi...
Figure S1. Gating strategy for CDCP1 flow cytometric analysis. Flow cytometric analysis of MDA-MB-23...
Figure S4. IKKε and p52 or MEK supports viability in LA conditions in at least two TNBC lines. Growt...
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...
Table S1. IC50 values for selected inhibitors in breast cancer lines. IC50 values obtained in the cu...
Figure S3. IKKε inhibits activity of p52. qRT-PCR and ChIP-PCR results for MDA MB 231 cell line and ...
Figure S2. The MEK inhibitor PD98059 and the PI3K inhibitor Wortmannin prevent respectively the acti...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...
Figure S2. Knockdown of IKKε leads to increased expression of non-canonical NF-kB proteins in at lea...
Silencing SHP2 expression in the MDA-MB-231 (a) and MDA-MB-468 (b) cells drastically reduced EGFR pr...
Figure S1. miR-140-3p-1 modestly inhibits proliferation of breast preneoplastic cells. (A) Immunoflu...
Inhibition of NF-κB p65 affects FOXC1 protein levels. MDA-MB-468 cells were serum-starved overnight ...
FC-IBC02 cell proliferation assays: estimated time trends in response to different CEP-37440 concent...
Figure S1. RTK expression and ERBB2-targeting antibody response in breast cancer cell lines. Figure ...
Figure S1. The PI3K/AKT pathway significantly contributes to the ligand-driven HER2 signaling activi...
Figure S1. Gating strategy for CDCP1 flow cytometric analysis. Flow cytometric analysis of MDA-MB-23...