Genes and variants not considered in current drug response predictions. (XLSX 36 kb
The non-redundant resistance genes in the filtered version of the FARME database used for this study...
Number of training cell lines (nTrain), prevalence of gene mutation, p-values, number of test set ce...
Genes prediction for orphan reactions. In a separate excel file, which can also be downloaded from: ...
Table S1. Significant predictive power of different subsets of resistance genes on known mobile anti...
Table S2. List of current drug indications with a significant overlap between genes significantly up...
Table S2. Commonly used target genes for qPCR-based studies of resistance genes in the environments ...
Mean number of individuals mutated for different types of protein domains. We calculated the mean nu...
Table S3. Drug repositioning hypotheses based on the significance of the overlap between genes genet...
Table S1. List of diseases with a significant overlap between genes differentially expressed and gen...
Table S3. Significant predictive power of different subsets of resistance genes on antibiotic resist...
Collection of drug modules in GMT format. The first column indicates the name of the drug while the ...
Supplementary methods. Includes derivation of equations and math used for calculating the significan...
Validations of predicted drug-disease associations from the literature. (XLS 38Â kb
Additional file 1: Supplementary Tables. Table S1. Variant grouping strategies of 48 Interleukin-1 p...
Additional file 1: Supplementary Tables. Table S1. Variant grouping strategies of 48 Interleukin-1 p...
The non-redundant resistance genes in the filtered version of the FARME database used for this study...
Number of training cell lines (nTrain), prevalence of gene mutation, p-values, number of test set ce...
Genes prediction for orphan reactions. In a separate excel file, which can also be downloaded from: ...
Table S1. Significant predictive power of different subsets of resistance genes on known mobile anti...
Table S2. List of current drug indications with a significant overlap between genes significantly up...
Table S2. Commonly used target genes for qPCR-based studies of resistance genes in the environments ...
Mean number of individuals mutated for different types of protein domains. We calculated the mean nu...
Table S3. Drug repositioning hypotheses based on the significance of the overlap between genes genet...
Table S1. List of diseases with a significant overlap between genes differentially expressed and gen...
Table S3. Significant predictive power of different subsets of resistance genes on antibiotic resist...
Collection of drug modules in GMT format. The first column indicates the name of the drug while the ...
Supplementary methods. Includes derivation of equations and math used for calculating the significan...
Validations of predicted drug-disease associations from the literature. (XLS 38Â kb
Additional file 1: Supplementary Tables. Table S1. Variant grouping strategies of 48 Interleukin-1 p...
Additional file 1: Supplementary Tables. Table S1. Variant grouping strategies of 48 Interleukin-1 p...
The non-redundant resistance genes in the filtered version of the FARME database used for this study...
Number of training cell lines (nTrain), prevalence of gene mutation, p-values, number of test set ce...
Genes prediction for orphan reactions. In a separate excel file, which can also be downloaded from: ...