Evaluation of lung inflammatory response at days 3, 7, and 10.

<p>(A-D) BALF collected from Cre+ and Cre- mice at day 3 following bleomycin administration revealed no significant difference in BALF WBC, RBC, total protein, or cell differential. (E-K) BALF collected from Cre+ and Cre- mice at day 7 following bleomycin administration revealed no significant difference in BALF WBC, RBC, total protein, and cell differential. Measurements of select inflammatory cytokines in BALF revealed elevation of CXCL1 in Cre+ compared to Cre- animals but no difference in CXCL10 or MCP-1 (mean±SEM, n≥7). (L-R) BALF analysis at day 10 following bleomycin induced lung injury revealed no significant difference in BALF WBC, RBC, total protein, cell differential, or levels of CXCL1, CXCL10, and MCP-1 (mean±SEM, n≥7).