In the top panels, we compare different physical properties for yeast (red) and drosophila (blue) chromosomes at a nucleosomal resolution of 200 <i>bp</i> (reference model).

<p>In the bottom panel, we compare the reference model (Φ₀ = 0.043) with one possible coarse-grained model (<i>CG</i> = 10 kbp, Φ = 0.97) for the drosophila case. (a,d) Individual MSD <i>g</i>₁(<i>t</i>) (top curves), and center of mass MSD <i>g</i>₃(<i>t</i>) (bottom curves) as a function of time <i>t</i>. (b,e) The average physical squared distance 〈<i>R</i>²(<i>s</i>)〉 between any two monomers as a function of their linear distance <i>s</i> along the chain (given in <i>bp</i>). (c,f) Average contact probability <i>P</i>_<i>c</i>(<i>s</i>) as a function of <i>s</i>. A contact between any two monomers is defined if the 3D distance is less than a threshold <i>d</i>_<i>c</i> (with <i>d</i>_<i>c</i> = 55 <i>nm</i> in (c) and <i>d</i>_<i>c</i> = 163 <i>nm</i> in (f)). In (e,f), averages were computed over the same real time window (100 <i>sec</i> − 30 <i>min</i>). The error bars in (a, b, c) were computed as the standard deviation of the mean. Error bars in (a) are of the similar size of the symbols. For the yeast case, we fix <i>L</i>/<i>L</i>_<i>e</i> = 0.8, <i>ρ</i> = 0.005<i>bp</i>/<i>nm</i>³, and for drosophila, <i>L</i>/<i>L</i>_<i>e</i> = 70, <i>ρ</i> = 0.009<i>bp</i>/<i>nm</i>³ (see section ‘A reference model for chromosome’).