Frequency of rifampicin/isoniazid-resistance conferring mutations in the circulating M. tuberculosis genotypes/sub-lineages in Uganda (2009–2011).

Use of the GenoType® MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda

Bazira, J.
Asiimwe, B.B.
Joloba, M.L.
Bwanga, F.
Matee, M.I.

January 2010

Background: Drug resistance levels and patterns among Mycobacterium tuberculosis isolates from newly...

Elucidating Emergence and Transmission of Multidrug-Resistant Tuberculosis in Treatment Experienced Patients by Whole Genome Sequencing

Clark Taane G.
Mallard Kim
Coll Francesc
Preston Mark
Assefa Samuel
Harris David
Ogwang Sam
Mumbowa Francis
Kirenga Bruce
O’Sullivan Denise M.
Okwera Alphonse
Eisenach Kathleen D.
Joloba Moses
Bentley Stephen D.
Ellner Jerrold J.
Parkhill Julian
Jones-López Edward C.
McNerney Ruth

December 2013

strains isolated from treatment experienced patients with MDR-TB in Uganda over a period of four ye...

Molecular epidemiology and prevalence of mutations conferring rifampicin and isoniazid resistance in Mycobacterium tuberculosis strains from the southern Ukraine

Nikolayevskyy, V.V.
Brown, T.J.
Bazhora, Y.I.
Asmolov, A.A.
Balabanova, Y.M.
Drobniewski, F.A.

February 2007

AbstractUnderstanding the molecular epidemiology of tuberculosis (TB) and mutations in genes associa...

Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda

Edgar Kigozi (724127)
George W. Kasule (5318114)
Kenneth Musisi (440368)
Deus Lukoye (357718)
Samuel Kyobe (133439)
Fred Ashaba Katabazi (133433)
Eddie M. Wampande (5318117)
Moses L. Joloba (221691)
David Patrick Kateete (133432)

May 2018

<div>BackgroundAccurate diagnosis of tuberculosis, especially by using rapid molecular ass...

Frequency and patterns of resistance conferring mutations in M. tuberculosis isolates that were resistant to rifampicin (n = 45) and isoniazid (n = 50).

Edgar Kigozi (724127)
George W. Kasule (5318114)
Kenneth Musisi (440368)
Deus Lukoye (357718)
Samuel Kyobe (133439)
Fred Ashaba Katabazi (133433)
Eddie M. Wampande (5318117)
Moses L. Joloba (221691)
David Patrick Kateete (133432)

May 2018

Frequency and patterns of resistance conferring mutations in M. tuberculosis isolat...

Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda.

Edgar Kigozi
George W Kasule
Kenneth Musisi
Deus Lukoye
Samuel Kyobe
Fred Ashaba Katabazi
Eddie M Wampande
Moses L Joloba
David Patrick Kateete

January 2018

BACKGROUND:Accurate diagnosis of tuberculosis, especially by using rapid molecular assays, can reduc...

The occurrence and frequency of genomic mutations that mediate Isoniazid and Rifampicin resistance in Mycobacterium tuberculosis isolates from untreated pulmonary Tuberculosis cases in urban Blantyre, Malawi

Kumwenda, Geoffrey P.
Chipungu, Geoffrey
Sloan, Derek J.
Kaimila, Yankho
Chiumya, Kondwani
Pangani, Harry

March 2018

BackgroundThe emergence and spread of drug-resistant Tuberculosis (TB) is a major public health thre...

Whole genome sequencing to complement tuberculosis drug resistance surveys in Uganda

Ssengooba, Willy
Meehan, Conor J.
Lukoye, Deus
Kasule, George William
Musisi, Kenneth
Joloba, Moses L.
Cobelens, Frank G.
de Jong, Bouke C.

June 2016

AbstractUnderstanding the circulating Mycobacterium tuberculosis resistance mutations is vital for b...

Molecular characterisation of second-line drug resistance among drug resistant tuberculosis patients tested in Uganda: a two and a half-year's review.

Mujuni, Dennis
Kasemire, Dianah Linda
Ibanda, Ivan
Kabugo, Joel
Nsawotebba, Andrew
Phelan, Jody E
Majwala, Robert Kaos
Tugumisirize, Didas
Nyombi, Abdunoor
Orena, Beatrice
Turyahabwe, Irene
Byabajungu, Henry
Nadunga, Diana
Musisi, Kenneth
Joloba, Moses Lutakoome
Ssengooba, Willy

April 2022

BACKGROUND: Second-line drug resistance (SLD) among tuberculosis (TB) patients is a serious emerging...

The occurrence and frequency of genomic mutations that mediate Isoniazid and Rifampicin resistance in Mycobacterium tuberculosis isolates from untreated pulmonary Tuberculosis cases in urban Blantyre, Malawi

Kumwenda, Geoffrey
Chipungu, Geoffrey
Sloan, Derek
Kaimila, Yankho
Chiumya, Kondwani
Pangani, Harry

March 2018

Background The emergence and spread of drug-resistant Tuberculosis (TB) is a major public health thr...

Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in South-Western Uganda

Bazira, J.
Asiimwe, B.B
Joloba, M.L
Bwanga, F.
Matee, M.I

January 2011

Background: Determination of the prevalence and drug susceptibility of the M. tuberculosis strains i...

Genetic mutations at rifampicin resistance-determining region of RpoB gene in conferring resistance to isolated multidrug-resistant tuberculosis strains

Prasanta Kumar Das
Somtirtha B Ganguly
Bodhisatya Mandal

January 2018

Introduction: Drug resistant tuberculosis (TB) among the new and retreatment cases was seen to be 5%...

Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda.

Eddie M Wampande
Peter Naniima
Ezekiel Mupere
David P Kateete
LaShaunda L Malone
Catherine M Stein
Harriet Mayanja-Kizza
Sebastien Gagneux
W Henry Boom
Moses L Joloba

January 2019

BackgroundLimited data existed exclusively describing Mycobacterium tuberculosis lineage 3 (MTB-L3),...

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda.

Resty Naluyange
Gerald Mboowa
Kevin Komakech
Derrick Semugenze
David Patrick Kateete
Willy Ssengooba

January 2020

INTRODUCTION:Susceptibility testing for pyrazinamide (PZA), a cornerstone anti-TB drug is not common...

Rifampicin resistance conferring mutations among Mycobacterium tuberculosis strains in Rwanda

Cuella Martin, Isabel
Ngabonziza, Semuto
Torrea, Gabriela
Meehan, Conor Joseph
Mulders, Wim
Ushizimpumu, Bertin
De Weerdt, Louise
Keysers, Jelle
De Rijk, Willem Bram
Decroo, Tom
De Jong, Bouke
Rigouts, Leen

January 2023

Abstract: BACKGROUND The World Health Organization-endorsed phenotypic and genotypic drug-susceptibi...

Use of the GenoType® MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda

Bazira, J.
Asiimwe, B.B.
Joloba, M.L.
Bwanga, F.
Matee, M.I.

January 2010

Background: Drug resistance levels and patterns among Mycobacterium tuberculosis isolates from newly...

Elucidating Emergence and Transmission of Multidrug-Resistant Tuberculosis in Treatment Experienced Patients by Whole Genome Sequencing

Clark Taane G.
Mallard Kim
Coll Francesc
Preston Mark
Assefa Samuel
Harris David
Ogwang Sam
Mumbowa Francis
Kirenga Bruce
O’Sullivan Denise M.
Okwera Alphonse
Eisenach Kathleen D.
Joloba Moses
Bentley Stephen D.
Ellner Jerrold J.
Parkhill Julian
Jones-López Edward C.
McNerney Ruth

December 2013

strains isolated from treatment experienced patients with MDR-TB in Uganda over a period of four ye...

Molecular epidemiology and prevalence of mutations conferring rifampicin and isoniazid resistance in Mycobacterium tuberculosis strains from the southern Ukraine

Nikolayevskyy, V.V.
Brown, T.J.
Bazhora, Y.I.
Asmolov, A.A.
Balabanova, Y.M.
Drobniewski, F.A.

February 2007

AbstractUnderstanding the molecular epidemiology of tuberculosis (TB) and mutations in genes associa...

Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda

Edgar Kigozi (724127)
George W. Kasule (5318114)
Kenneth Musisi (440368)
Deus Lukoye (357718)
Samuel Kyobe (133439)
Fred Ashaba Katabazi (133433)
Eddie M. Wampande (5318117)
Moses L. Joloba (221691)
David Patrick Kateete (133432)

May 2018

<div>BackgroundAccurate diagnosis of tuberculosis, especially by using rapid molecular ass...

Frequency and patterns of resistance conferring mutations in M. tuberculosis isolates that were resistant to rifampicin (n = 45) and isoniazid (n = 50).

Edgar Kigozi (724127)
George W. Kasule (5318114)
Kenneth Musisi (440368)
Deus Lukoye (357718)
Samuel Kyobe (133439)
Fred Ashaba Katabazi (133433)
Eddie M. Wampande (5318117)
Moses L. Joloba (221691)
David Patrick Kateete (133432)

May 2018

Frequency and patterns of resistance conferring mutations in M. tuberculosis isolat...

Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda.

Edgar Kigozi
George W Kasule
Kenneth Musisi
Deus Lukoye
Samuel Kyobe
Fred Ashaba Katabazi
Eddie M Wampande
Moses L Joloba
David Patrick Kateete

January 2018

BACKGROUND:Accurate diagnosis of tuberculosis, especially by using rapid molecular assays, can reduc...

The occurrence and frequency of genomic mutations that mediate Isoniazid and Rifampicin resistance in Mycobacterium tuberculosis isolates from untreated pulmonary Tuberculosis cases in urban Blantyre, Malawi

Kumwenda, Geoffrey P.
Chipungu, Geoffrey
Sloan, Derek J.
Kaimila, Yankho
Chiumya, Kondwani
Pangani, Harry

March 2018

BackgroundThe emergence and spread of drug-resistant Tuberculosis (TB) is a major public health thre...

Whole genome sequencing to complement tuberculosis drug resistance surveys in Uganda

Ssengooba, Willy
Meehan, Conor J.
Lukoye, Deus
Kasule, George William
Musisi, Kenneth
Joloba, Moses L.
Cobelens, Frank G.
de Jong, Bouke C.

June 2016

AbstractUnderstanding the circulating Mycobacterium tuberculosis resistance mutations is vital for b...

Molecular characterisation of second-line drug resistance among drug resistant tuberculosis patients tested in Uganda: a two and a half-year's review.

Mujuni, Dennis
Kasemire, Dianah Linda
Ibanda, Ivan
Kabugo, Joel
Nsawotebba, Andrew
Phelan, Jody E
Majwala, Robert Kaos
Tugumisirize, Didas
Nyombi, Abdunoor
Orena, Beatrice
Turyahabwe, Irene
Byabajungu, Henry
Nadunga, Diana
Musisi, Kenneth
Joloba, Moses Lutakoome
Ssengooba, Willy

April 2022

BACKGROUND: Second-line drug resistance (SLD) among tuberculosis (TB) patients is a serious emerging...

The occurrence and frequency of genomic mutations that mediate Isoniazid and Rifampicin resistance in Mycobacterium tuberculosis isolates from untreated pulmonary Tuberculosis cases in urban Blantyre, Malawi

Kumwenda, Geoffrey
Chipungu, Geoffrey
Sloan, Derek
Kaimila, Yankho
Chiumya, Kondwani
Pangani, Harry

March 2018

Background The emergence and spread of drug-resistant Tuberculosis (TB) is a major public health thr...

Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in South-Western Uganda

Bazira, J.
Asiimwe, B.B
Joloba, M.L
Bwanga, F.
Matee, M.I

January 2011

Background: Determination of the prevalence and drug susceptibility of the M. tuberculosis strains i...

Genetic mutations at rifampicin resistance-determining region of RpoB gene in conferring resistance to isolated multidrug-resistant tuberculosis strains

Prasanta Kumar Das
Somtirtha B Ganguly
Bodhisatya Mandal

January 2018

Introduction: Drug resistant tuberculosis (TB) among the new and retreatment cases was seen to be 5%...

Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda.

Eddie M Wampande
Peter Naniima
Ezekiel Mupere
David P Kateete
LaShaunda L Malone
Catherine M Stein
Harriet Mayanja-Kizza
Sebastien Gagneux
W Henry Boom
Moses L Joloba

January 2019

BackgroundLimited data existed exclusively describing Mycobacterium tuberculosis lineage 3 (MTB-L3),...

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda.

Resty Naluyange
Gerald Mboowa
Kevin Komakech
Derrick Semugenze
David Patrick Kateete
Willy Ssengooba

January 2020

INTRODUCTION:Susceptibility testing for pyrazinamide (PZA), a cornerstone anti-TB drug is not common...

Rifampicin resistance conferring mutations among Mycobacterium tuberculosis strains in Rwanda

Cuella Martin, Isabel
Ngabonziza, Semuto
Torrea, Gabriela
Meehan, Conor Joseph
Mulders, Wim
Ushizimpumu, Bertin
De Weerdt, Louise
Keysers, Jelle
De Rijk, Willem Bram
Decroo, Tom
De Jong, Bouke
Rigouts, Leen

January 2023

Abstract: BACKGROUND The World Health Organization-endorsed phenotypic and genotypic drug-susceptibi...

Use of the GenoType® MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda

Bazira, J.
Asiimwe, B.B.
Joloba, M.L.
Bwanga, F.
Matee, M.I.

January 2010

Background: Drug resistance levels and patterns among Mycobacterium tuberculosis isolates from newly...

Elucidating Emergence and Transmission of Multidrug-Resistant Tuberculosis in Treatment Experienced Patients by Whole Genome Sequencing

Clark Taane G.
Mallard Kim
Coll Francesc
Preston Mark
Assefa Samuel
Harris David
Ogwang Sam
Mumbowa Francis
Kirenga Bruce
O’Sullivan Denise M.
Okwera Alphonse
Eisenach Kathleen D.
Joloba Moses
Bentley Stephen D.
Ellner Jerrold J.
Parkhill Julian
Jones-López Edward C.
McNerney Ruth

December 2013

strains isolated from treatment experienced patients with MDR-TB in Uganda over a period of four ye...

Molecular epidemiology and prevalence of mutations conferring rifampicin and isoniazid resistance in Mycobacterium tuberculosis strains from the southern Ukraine

Nikolayevskyy, V.V.
Brown, T.J.
Bazhora, Y.I.
Asmolov, A.A.
Balabanova, Y.M.
Drobniewski, F.A.

February 2007

AbstractUnderstanding the molecular epidemiology of tuberculosis (TB) and mutations in genes associa...

Frequency of rifampicin/isoniazid-resistance conferring mutations in the circulating <i>M</i>. <i>tuberculosis</i> genotypes/sub-lineages in Uganda (2009–2011).

Abstract

Extracted data

Frequency of rifampicin/isoniazid-resistance conferring mutations in the circulating <i>M</i>. <i>tuberculosis</i> genotypes/sub-lineages in Uganda (2009–2011).

Abstract

Extracted data

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