Proportionality between the excitatory and inhibitory currents and the firing rate in the experiment.

<p>(<b>A</b>) Upper trace: A representative recording of glutamatergic synaptic activity in the voltage-clamp mode at the reversal potential of GABA-mediated currents (<i>V</i>_<i>hold</i> = <i>V</i>_<i>GABA</i> = −51<i>mV</i>). Lower trace: A corresponding firing activity of the neighboring neuron recorded in the cell-attached voltage-clamp mode. (<b>B</b>) The recordings from the same pair of neurons as in A. The upper trace was recorded at the reversal potential of glutamate-mediated currents (<i>V</i>_<i>hold</i> = <i>V</i>_<i>Glut</i> = 0) and represents the GABAergic synaptic activity. The yellow shadow indicates the IDs. (<b>C</b>) Several superimposed IID-like events from A (left) and B (right) that correspond to SBs and constitute IDs. (<b>D</b>) Pooled data from four IDs, each consisting of 50–80 SBs as in C. A histogram represents the firing rate of the neuron recorded in the cell-attached VC mode. Solid lines are the plots of GABA- and glutamate-mediated currents scaled to represent the synaptic input at the membrane potential of -40 mV.