<p>Collagen Col1A1 (<b>A</b>), TGFβ (<b>B</b>), IL-1β (<b>C</b>), IL-2 (<b>D</b>), IL-6 (<b>E</b>) and IL-10 (<b>F</b>) protein levels in whole lung tissue lysates obtained from C57BL/6 mice 21 days after endotracheal injection of sterile saline (saline) or bleomycin (bleo), the latter also followed by intravenous infusion of hUC-MSC (bleo+hUC-MSC) or sterile saline (bleo+saline). Results are representative of three independent experiments. Densitometric analysis of protein bands is normalized to actin and expressed as mean ± SD (n = 5 per group). ** = P < 0.01, *** = P < 0.001 compared to bleomycin treated mice.</p
<p>Lung lavage fluid was obtained from the right lung after 240 min of ventilation and analyzed by E...
<p>Peripheral lung tissue samples from IPF (n=16) and controls (n=6-8, 6 lung donors plus additional...
<p>WT and transgenic mice were injected intravenously with saline or BLM and sacrificed at indicated...
<p>Gene expression analysis of Col1A1 (<b>A</b>), TGFβ (<b>B</b>), α-SMA (<b>C</b>), IL-1β (<b>D</b>...
Expression of (A) IL-6 and IL-1β proteins in the lung tissue of Balb/c mice that received PBS, B19V-...
<p><b>A</b>: TGFβ increases after bleomycin-induced lung injury only in wildtype mice, whereas knock...
Subsequently, mice were euthanized and lungs were examined histopathologically as described in Mater...
<p>Representative results of H&E staining of lung tissue from mice in the bleomycin-induced lung inj...
<p>Immunoperoxidase demonstration of AQP-5 (A) and Sirius Red staining (B) of wild type and <i>P2rx7...
<p>Collagen content in mouse lungs 8 days (<b>A-D</b>), 14 days (<b>E-H</b>) and 21 days (<b>I-L</b>...
<p>Histology (<b>A-B</b>), collagen content (<b>C-D</b>) and macrophage infiltration (<b>E-H</b>) of...
<p>IL-1β, TGF-β, TNF-α, IFN-γ, IL-17A levels were measured by ELISA in (<b>A</b>) BAL fluid or in (<...
<p>(A) The MLF were isolated from TERT CKO or WT mice at 21 days after BLM injection, and analyzed f...
<p>5-LO protein in mice lung homogenates was determined by Western blotting A. Representative blots....
<p>The lungs (A-E) and BALF (F-I) were collected from mice on day 33 after starting saline or bleomy...
<p>Lung lavage fluid was obtained from the right lung after 240 min of ventilation and analyzed by E...
<p>Peripheral lung tissue samples from IPF (n=16) and controls (n=6-8, 6 lung donors plus additional...
<p>WT and transgenic mice were injected intravenously with saline or BLM and sacrificed at indicated...
<p>Gene expression analysis of Col1A1 (<b>A</b>), TGFβ (<b>B</b>), α-SMA (<b>C</b>), IL-1β (<b>D</b>...
Expression of (A) IL-6 and IL-1β proteins in the lung tissue of Balb/c mice that received PBS, B19V-...
<p><b>A</b>: TGFβ increases after bleomycin-induced lung injury only in wildtype mice, whereas knock...
Subsequently, mice were euthanized and lungs were examined histopathologically as described in Mater...
<p>Representative results of H&E staining of lung tissue from mice in the bleomycin-induced lung inj...
<p>Immunoperoxidase demonstration of AQP-5 (A) and Sirius Red staining (B) of wild type and <i>P2rx7...
<p>Collagen content in mouse lungs 8 days (<b>A-D</b>), 14 days (<b>E-H</b>) and 21 days (<b>I-L</b>...
<p>Histology (<b>A-B</b>), collagen content (<b>C-D</b>) and macrophage infiltration (<b>E-H</b>) of...
<p>IL-1β, TGF-β, TNF-α, IFN-γ, IL-17A levels were measured by ELISA in (<b>A</b>) BAL fluid or in (<...
<p>(A) The MLF were isolated from TERT CKO or WT mice at 21 days after BLM injection, and analyzed f...
<p>5-LO protein in mice lung homogenates was determined by Western blotting A. Representative blots....
<p>The lungs (A-E) and BALF (F-I) were collected from mice on day 33 after starting saline or bleomy...
<p>Lung lavage fluid was obtained from the right lung after 240 min of ventilation and analyzed by E...
<p>Peripheral lung tissue samples from IPF (n=16) and controls (n=6-8, 6 lung donors plus additional...
<p>WT and transgenic mice were injected intravenously with saline or BLM and sacrificed at indicated...