<p>Gene expression analysis of Col1A1 (<b>A</b>), TGFβ (<b>B</b>), α-SMA (<b>C</b>), IL-1β (<b>D</b>), IL-2 (<b>E</b>), IL-6 (<b>F</b>) and IL-10 (<b>G</b>) in whole lung mRNA obtained at days 8, 14 and 21 after endotracheal injection of sterile saline (saline) or bleomycin (bleomycin), the latter also followed by intravenous infusion of hUC-MSC (bleomycin+hUC-MSC) or sterile saline (bleomycin+saline). Results are expressed as mean ± SD (n = 5 per group) and are representative of three independent experiments performed in triplicate. * = P < 0.05, ** = P < 0.01 compared to bleomycin treated mice.</p
<p>(A) WT and α4Y991A mice were given an i.t. challenge with bleomycin (n = 8 mice / group), and who...
<p>Lung tissues were collected and homogenized for RNA isolation and QRT-PCR analysis was performed ...
<p>IL-1β, TGF-β, TNF-α, IFN-γ, IL-17A levels were measured by ELISA in (<b>A</b>) BAL fluid or in (<...
<p>Collagen Col1A1 (<b>A</b>), TGFβ (<b>B</b>), IL-1β (<b>C</b>), IL-2 (<b>D</b>), IL-6 (<b>E</b>) a...
<p><b>A</b>: TGFβ increases after bleomycin-induced lung injury only in wildtype mice, whereas knock...
<p>Histology (<b>A-B</b>), collagen content (<b>C-D</b>) and macrophage infiltration (<b>E-H</b>) of...
Pulmonary fibrosis (PF) is the most common and aggressive interstitial lung disease, characterized b...
<p>Evaluation of cytokine-induced neutrophil chemoattractant-1 (CINC-1; A), monocyte chemoattractant...
<p>Mice challenged with intratracheal bleomycin (0.05 U) on day 0 and dosed with SAP (6 mg/kg, i.p. ...
<p>C57BL/6 mice were inoculated with PBS (mock) or infected intranasally with 10<sup>5</sup> PFU inf...
<p>Samples from BAL extracts (A) and whole lung homogenates (B) were analyzed via protein array to d...
<p>Collagen content in mouse lungs 8 days (<b>A-D</b>), 14 days (<b>E-H</b>) and 21 days (<b>I-L</b>...
Additional file 4: Figure S4. SiRNA-IL-11 transiently transfection attenuates bleomycin-induced lung...
<p>(A) The MLF were isolated from TERT CKO or WT mice at 21 days after BLM injection, and analyzed f...
<p>Real-time quantitative PCR of genes mapping to the reduced <i>Blmpf2</i> region prior to (day 0: ...
<p>(A) WT and α4Y991A mice were given an i.t. challenge with bleomycin (n = 8 mice / group), and who...
<p>Lung tissues were collected and homogenized for RNA isolation and QRT-PCR analysis was performed ...
<p>IL-1β, TGF-β, TNF-α, IFN-γ, IL-17A levels were measured by ELISA in (<b>A</b>) BAL fluid or in (<...
<p>Collagen Col1A1 (<b>A</b>), TGFβ (<b>B</b>), IL-1β (<b>C</b>), IL-2 (<b>D</b>), IL-6 (<b>E</b>) a...
<p><b>A</b>: TGFβ increases after bleomycin-induced lung injury only in wildtype mice, whereas knock...
<p>Histology (<b>A-B</b>), collagen content (<b>C-D</b>) and macrophage infiltration (<b>E-H</b>) of...
Pulmonary fibrosis (PF) is the most common and aggressive interstitial lung disease, characterized b...
<p>Evaluation of cytokine-induced neutrophil chemoattractant-1 (CINC-1; A), monocyte chemoattractant...
<p>Mice challenged with intratracheal bleomycin (0.05 U) on day 0 and dosed with SAP (6 mg/kg, i.p. ...
<p>C57BL/6 mice were inoculated with PBS (mock) or infected intranasally with 10<sup>5</sup> PFU inf...
<p>Samples from BAL extracts (A) and whole lung homogenates (B) were analyzed via protein array to d...
<p>Collagen content in mouse lungs 8 days (<b>A-D</b>), 14 days (<b>E-H</b>) and 21 days (<b>I-L</b>...
Additional file 4: Figure S4. SiRNA-IL-11 transiently transfection attenuates bleomycin-induced lung...
<p>(A) The MLF were isolated from TERT CKO or WT mice at 21 days after BLM injection, and analyzed f...
<p>Real-time quantitative PCR of genes mapping to the reduced <i>Blmpf2</i> region prior to (day 0: ...
<p>(A) WT and α4Y991A mice were given an i.t. challenge with bleomycin (n = 8 mice / group), and who...
<p>Lung tissues were collected and homogenized for RNA isolation and QRT-PCR analysis was performed ...
<p>IL-1β, TGF-β, TNF-α, IFN-γ, IL-17A levels were measured by ELISA in (<b>A</b>) BAL fluid or in (<...