<p>The brains were collected after the experiment and the microglial cells isolated by the enzymatic digestion. The phagocytic activity against HF488- Aβ<sub>1–42</sub> in the microglial cells was measured using a flow cytometer as described in the Methods. No significant difference is observed between groups (one-way ANOVA followed by Tukey’s multiple-comparisons test). The box-whisker plots describe the minimum (end of the bottom whisker), the first quartile (bottom border of the box), the median (line through the box), the third quartile (top border of the box), and the maximum (end of the top whisker) of the distribution, <i>n</i> = 3–6.</p
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
<p>Sections from lesion sites were stained for Iba-1 (green) and DAPI (blue) at 3 and 14 dpi in both...
<p>(A) Microglial cells were treated with or without PQQ 1 h prior to 4 h co-treatment with LPS. The...
<p>We tested the capacity of microglia to phagocytose fluorescent-labeled latex beads by observing t...
<p>Representative photographs show Iba-1 immuno-stained microglia of the mouse brain (A). LPS group ...
<p>Images in (A–L) demonstrate immunoflourescence stainings of dendritic MHCII+ cells in the medial ...
<p>Microglial treatment conditions are indicated and are further described in <a href="http://www.pl...
<p>The brain concentrations of two soluble Aβs (A, B) and insoluble Aβs (C,D) are shown. Values are ...
Using immunocytochemistry with monoclonal antibodies against surface immunomolecules and Griffonia s...
Using immunocytochemistry with monoclonal antibodies against surface immunomolecules and Griffonia s...
The cellular uptake of FITC-dextran was determined by flow cytometry. (A) Flow data for the uptake b...
<p>(A) Representative images of NF-κB p65 in microglial cells of each group. Cells were pretreated w...
<p>Phagocytosis was measured according to fluorescent intensity of cell lysate from control or LPS a...
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
<p>Sections from lesion sites were stained for Iba-1 (green) and DAPI (blue) at 3 and 14 dpi in both...
<p>(A) Microglial cells were treated with or without PQQ 1 h prior to 4 h co-treatment with LPS. The...
<p>We tested the capacity of microglia to phagocytose fluorescent-labeled latex beads by observing t...
<p>Representative photographs show Iba-1 immuno-stained microglia of the mouse brain (A). LPS group ...
<p>Images in (A–L) demonstrate immunoflourescence stainings of dendritic MHCII+ cells in the medial ...
<p>Microglial treatment conditions are indicated and are further described in <a href="http://www.pl...
<p>The brain concentrations of two soluble Aβs (A, B) and insoluble Aβs (C,D) are shown. Values are ...
Using immunocytochemistry with monoclonal antibodies against surface immunomolecules and Griffonia s...
Using immunocytochemistry with monoclonal antibodies against surface immunomolecules and Griffonia s...
The cellular uptake of FITC-dextran was determined by flow cytometry. (A) Flow data for the uptake b...
<p>(A) Representative images of NF-κB p65 in microglial cells of each group. Cells were pretreated w...
<p>Phagocytosis was measured according to fluorescent intensity of cell lysate from control or LPS a...
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
International audienceWithin the central nervous system (CNS) the traditional role of microglia has ...
<p>Sections from lesion sites were stained for Iba-1 (green) and DAPI (blue) at 3 and 14 dpi in both...
<p>(A) Microglial cells were treated with or without PQQ 1 h prior to 4 h co-treatment with LPS. The...