Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants - Fig 1

<p><b>Comparison of the quantification of minority resistant variants (MRV) using SmartGene^® (SG) and AVA^® pipeline analysis for protease mutations (A,B) and Reverse Transcriptase (RT) (C, D) mutations after excluding two major discrepancies</b>. Minority resistant variants frequencies were depicted according to linear regression (A, C) and Bland-Altman (B, D) analyses. For Bland-Altman analysis, y-axis indicates the percentage of difference in MRV frequency measurements between AVA^® and SG^® analysis and x-axis indicates the mean of the two measurements. All MRV detected by both software were included in this analysis. The 95% confidence intervals limits of agreement were calculated. Mean, upper and lower limits of agreement were depicted by the dotted lines.