Pancreatic neutrophil infiltration during acute pancreatitis is receptor dependent.
- A. A. Alahmari (5340914)
- B. Sreekumar (5340896)
- V. Patel (5340902)
- M. Ashat (5340926)
- M. Alexandre (5340893)
- A. K. Uduman (5340911)
- E. O. Akinbiyi (5340905)
- A. Ceplenski (5340899)
- C. A. Shugrue (5340929)
- T. R. Kolodecik (5340932)
- N. Tashkandi (5340908)
- S. W. Messenger (5340890)
- G. E. Groblewski (5340920)
- F. S. Gorelick (5340923)
- E. C. Thrower (5340917)
Publication date
June 2018
DOIAbstract
<p>NNK caused neutrophil infiltration in WT but not <i>α</i>7nAChR<sup>-/-</sup> mice. Also, knocking out <i>α</i>7nAChR decreases neutrophils migration into CER-treated pancreatic tissues, and this effect was more intense when NNK was given in combination with CER. Studies in wild type and <i>α</i>7nAChR<sup>-/-</sup> (KO) mice. Values are means ± SE; n ≥ 4. *P < 0.05 vs. PBS WT. #P < 0.05 vs. analogous WT.</p
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