Additional file 3: of Proteomic analysis of Medulloblastoma reveals functional biology with translational potential

Figure S1. Correlation between mRNA and protein abundance by subgroups. a) Frequency distribution plots of mRNA-protein spearman’s correlations for each medulloblastoma subgroup. Positive mRNA-protein correlations were found for 68–80% of mRNA-protein pairs with means between (0.30–0.16) depending on the subgroup. However, just a small proportion of them were significant (10–17%). Group 3 was the subgroup with the highest number of significant positive correlations and the highest mean; in contrast, group 4 had the lowest mean. b) Box-plots depicting the distribution of mRNA-protein Spearman’s correlations by subgroup. p-values for differences between the subgroups were calculated with the Kruskal-Wallis rank-sum test. p-values indicating the differences between group 4 and the others were calculated with a two-sided Wilcoxon rank sum test. (PDF 706 kb