Changes in neutralizing antibody titers and phenotypic/functional memory-related biomarkers at distinct time-points after primary 17DD-YF vaccination.
- Christiane Costa-Pereira (5348894)
- Ana Carolina Campi-Azevedo (294819)
- Jordana Grazziela Coelho-dos-Reis (5348879)
- Vanessa Peruhype-Magalhães (437199)
- Márcio Sobreira Silva Araújo (3074373)
- Lis Ribeiro do Vale Antonelli (5224127)
- Cristina Toscano Fonseca (696496)
- Jandira Aparecida Lemos (5348900)
- Luiz Cosme Cote Malaquias (5348906)
- Matheus de Souza Gomes (3772336)
- Laurence Rodrigues Amaral (5224136)
- Maria Rios (198701)
- Caren Chancey (416700)
- Harold Richard Persi (5348891)
- Jorge Marcelo Pereira (5348909)
- Maria de Lourdes de Sousa Maia (294828)
- Marcos da Silva Freire (294830)
- Reinaldo de Menezes Martins (294827)
- Akira Homma (294831)
- Marisol Simões (5348882)
- Anna Yoshida Yamamura (5348903)
- Roberto Henrique Guedes Farias (294829)
- Alessandro Pecego Martins Romano (534766)
- Carla Magda Domingues (5348888)
- Pedro Luiz Tauil (5348885)
- Pedro Fernando Costa Vasconcelos (5348897)
- Iramaya Rodrigues Caldas (294836)
- Luiz Antônio Camacho (5348912)
- Andrea Teixeira-Carvalho (259890)
- Olindo Assis Martins-Filho (294842)
Publication date
June 2018
DOIAbstract
<p>Correlation analyses were performed to validate the time-dependent decline in (A) neutralizing antibody titers and 17DD-YF Memory-related (B) phenotypic and (C) functional features. Data are expressed as scattering distribution of individual values along distinct time-points after 17DD-YF primary vaccination against neutralizing antibody titers (PRNT) as well as phenotypic and functional features (YF-Ag/CC Index). Spearman’s correlation test was applied to identify significant time-dependent loss of memory-related biomarkers. Correlation indices (p and r) along with the 95% confidence band of the best-fit line are provided in the figure. Attributes with higher correlation indices (r values) are highlighted with gray background.</p
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