SEM for IC/BPS bladder samples.

<p>SEM of IC/BPS specimens showed umbrella cell pleomorphism (A, bar: 40um) and denudation with intermediate cell exposure (B, arrowhead, bar: 100um). In some severe IC/BPS, totally denudation of urothelium with exposed basement membrane was observed (C,bar 20um). In some patients, microplicae of the umbrella cell membranes was only mild decreased (D, bar: 2um), but most patients had moderate to severe decreases of microplicae (E, bar: 2um and F, bar: 5um).