Additional file 2: of Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer
- Ricardo Ribas (222948)
- Sunil Pancholi (222942)
- Aradhana Rani (529007)
- Eugene Schuster (12754)
- Stephanie Guest (5350772)
- Joanna Nikitorowicz-Buniak (776212)
- Nikiana Simigdala (424363)
- Allan Thornhill (5350766)
- Francesca Avogadri-Connors (5350769)
- Richard Cutler (5350763)
- Alshad Lalani (5350775)
- Mitch Dowsett (645)
- Stephen Johnston (767275)
- Lesley-Ann Martin (222958)
Publication date
June 2018
DOIAbstract
Figure S2. Anti-proliferative effect of RAD001 in combination with endocrine agents (a) 4-OHT and (b) ICI. Endocrine-resistant and -sensitive BC cell lines were treated with a combination of RAD001 (3 nM) and increasing concentrations of (a) 4-OHT or (b) ICI for 6 days with media change at day 3. Cell viability was analysed using a cell titer-glo assay. Data are expressed as fold-change relative to vehicle control. Error bars represent mean ± SEM. (PDF 196 kb
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