Digitoxin affects mRNA processing and various signaling pathways related to cell division, signal transduction and cancer.
- Martin Liss (5368172)
- Michael H. Radke (5368175)
- Jamina Eckhard (370592)
- Martin Neuenschwander (680771)
- Vita Dauksaite (5368178)
- Jens-Peter von Kries (5368169)
- Michael Gotthardt (755019)
Publication date
June 2018
DOIAbstract
<p>Gene ontology according to WikiPathways analysis of transcripts differentially regulated by digitoxin in HEK293 suggest specific effects that include pathways related to growth and cell cycle as well as differential expression of > 60 genes involved in mRNA processing (adjusted <i>P</i> ≤ 0.05 [Benjamin-Hochberg], two-sided hypergeometric test).</p
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