Additional file 7: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

Publication date

June 2018

DOI

10.6084/m9.figshare.6529973.v1

Abstract

Figure S6. Control colony-forming assay results derived from non-tumor-bearing mice. Blood from non-tumor-bearing mice contained no cells that formed colonies. (PPTX 53Â kb

Extracted data

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Data Protection

Additional file 7: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

Open link

Publication date

June 2018

DOI

10.6084/m9.figshare.6529973.v1

Abstract

Figure S6. Control colony-forming assay results derived from non-tumor-bearing mice. Blood from non-tumor-bearing mice contained no cells that formed colonies. (PPTX 53Â kb

Extracted data

Linan Liu (715375)
Shirley Zhang (3568394)
Rangoli Aeran (3568391)
Wenbin Liao (3458729)
Mengrou Lu (3568397)
George Polovin (3568400)
Egest Pone (3568403)
Weian Zhao (715376)

September 2015

Engineered mesenchymal stem cell (hGluc-MSC) infusion has no influence on the growth of cancer metas...

Additional file 2: of Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment

María García-Mendoza (3514325)
David Inman (3514316)
Suzanne Ponik (3514313)
Justin Jeffery (3514328)
Dagna Sheerar (3514310)
Rachel Van Doorn (3514322)
Patricia Keely (3514319)

May 2016

Tumor mice complete blood counts at late tumor stages. A White blood cell, B lymphocyte, C monocyte,...

Additional file 4: of Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models

Rachel Sabol (6438179)
Annie Bowles (3505478)
Alex Côté (6727181)
Rachel Wise (6727184)
Benjamen O’Donnell (6727187)
Margarite Matossian (6040496)
Fokhrul Hossain (6040487)
Hope Burks (6438176)
Luis Valle (6727190)
Lucio Miele (81383)
Bridgette Collins-Burow (444016)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

May 2019

Figure S4. Flow cytometric analysis of PDX tumor shows obASCs promote EMT and increase classically a...

Additional file 5: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S4. OSM is highly expressed in orthotopic 4T1.2 primary mammary tumors in female BALB/c mice....

Additional file 8: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S7. Test of cell line-specific variance in colony-forming assay between 4T1.2-shLacZ and 4T1....

Additional file 9: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S8. OSM inhibits proliferation of 4T1.2 cells. One hundred 4T1.2 cells were plated at day 0 a...

Additional file 3: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S2. Representative OSM staining intensity in IHC. 0 = no staining (image not shown), 1 = ligh...

Additional file 6: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S5. qPCR analysis of lung metastases after intracardiac injections. 4T1.2-shLacZ cells and 4T...

Additional file 1: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Table S1. Primer and probe sequences used for qPCR assay for the detection of CTC in blood obtained ...

Additional file 4: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S3. Deterioration of physical condition in MDATO/OSM tumor-bearing mice treated with TET. a M...

Additional file 1: of Osthole inhibits triple negative breast cancer cells by suppressing STAT3

Xuanxuan Dai (4421281)
Changtian Yin (4421287)
Yi Zhang (9093)
Guilong Guo (4421284)
Chengguang Zhao (4221556)
Ouchen Wang (217737)
Youqun Xiang (6113663)
Xiaohua Zhang (350570)
Guang Liang (206236)

December 2018

Figure S1. showed nuclear morphology of TNBC cells exposed to osthole and Figure S2. showed no toxic...

Additional file 3: of Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases

Colleen Chute (5486414)
Xinhai Yang (20940)
Kristy Meyer (5486408)
Ning Yang (114965)
Keelin O’Neil (5486417)
Ildiko Kasza (5486411)
Kevin Eliceiri (3185430)
Caroline Alexander (310292)
Andreas Friedl (128704)

July 2018

Figure S3. Effect of host Sdc1 on later stages of E0771 carcinoma cell metastasis. E0771 tumor cells...

Additional file 4: Figure S4. of Exogenous marker-engineered mesenchymal stem cells detect cancer and metastases in a simple blood assay

Linan Liu (715375)
Shirley Zhang (3568394)
Rangoli Aeran (3568391)
Wenbin Liao (3458729)
Mengrou Lu (3568397)
George Polovin (3568400)
Egest Pone (3568403)
Weian Zhao (715376)

September 2015

Engineered mesenchymal stem cell (hGluc-MSC) infusion has no influence on the growth of cancer metas...

Additional file 2: of Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment

María García-Mendoza (3514325)
David Inman (3514316)
Suzanne Ponik (3514313)
Justin Jeffery (3514328)
Dagna Sheerar (3514310)
Rachel Van Doorn (3514322)
Patricia Keely (3514319)

May 2016

Tumor mice complete blood counts at late tumor stages. A White blood cell, B lymphocyte, C monocyte,...

Rachel Sabol (6438179)
Annie Bowles (3505478)
Alex Côté (6727181)
Rachel Wise (6727184)
Benjamen O’Donnell (6727187)
Margarite Matossian (6040496)
Fokhrul Hossain (6040487)
Hope Burks (6438176)
Luis Valle (6727190)
Lucio Miele (81383)
Bridgette Collins-Burow (444016)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

May 2019

Figure S4. Flow cytometric analysis of PDX tumor shows obASCs promote EMT and increase classically a...

Additional file 5: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S4. OSM is highly expressed in orthotopic 4T1.2 primary mammary tumors in female BALB/c mice....

Additional file 8: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S7. Test of cell line-specific variance in colony-forming assay between 4T1.2-shLacZ and 4T1....

Additional file 9: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S8. OSM inhibits proliferation of 4T1.2 cells. One hundred 4T1.2 cells were plated at day 0 a...

Additional file 3: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S2. Representative OSM staining intensity in IHC. 0 = no staining (image not shown), 1 = ligh...

Additional file 6: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S5. qPCR analysis of lung metastases after intracardiac injections. 4T1.2-shLacZ cells and 4T...

Additional file 1: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Table S1. Primer and probe sequences used for qPCR assay for the detection of CTC in blood obtained ...

Additional file 4: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara (748035)
Celeste Bolin (5393150)
Jordan Koncinsky (5393135)
Sujatha Kadaba (5393144)
Hunter Covert (5393132)
Caleb Sutherland (3207948)
Laura Bond (3801250)
Joseph Kronz (5393147)
Joel Garbow (5393141)
Cheryl Jorcyk (5393138)

June 2018

Figure S3. Deterioration of physical condition in MDATO/OSM tumor-bearing mice treated with TET. a M...

Additional file 1: of Osthole inhibits triple negative breast cancer cells by suppressing STAT3

Xuanxuan Dai (4421281)
Changtian Yin (4421287)
Yi Zhang (9093)
Guilong Guo (4421284)
Chengguang Zhao (4221556)
Ouchen Wang (217737)
Youqun Xiang (6113663)
Xiaohua Zhang (350570)
Guang Liang (206236)

December 2018

Figure S1. showed nuclear morphology of TNBC cells exposed to osthole and Figure S2. showed no toxic...

Additional file 3: of Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases

Colleen Chute (5486414)
Xinhai Yang (20940)
Kristy Meyer (5486408)
Ning Yang (114965)
Keelin O’Neil (5486417)
Ildiko Kasza (5486411)
Kevin Eliceiri (3185430)
Caroline Alexander (310292)
Andreas Friedl (128704)

July 2018

Figure S3. Effect of host Sdc1 on later stages of E0771 carcinoma cell metastasis. E0771 tumor cells...

Additional file 4: Figure S4. of Exogenous marker-engineered mesenchymal stem cells detect cancer and metastases in a simple blood assay

Linan Liu (715375)
Shirley Zhang (3568394)
Rangoli Aeran (3568391)
Wenbin Liao (3458729)
Mengrou Lu (3568397)
George Polovin (3568400)
Egest Pone (3568403)
Weian Zhao (715376)

September 2015

Engineered mesenchymal stem cell (hGluc-MSC) infusion has no influence on the growth of cancer metas...

Additional file 2: of Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment

María García-Mendoza (3514325)
David Inman (3514316)
Suzanne Ponik (3514313)
Justin Jeffery (3514328)
Dagna Sheerar (3514310)
Rachel Van Doorn (3514322)
Patricia Keely (3514319)

May 2016

Tumor mice complete blood counts at late tumor stages. A White blood cell, B lymphocyte, C monocyte,...

Rachel Sabol (6438179)
Annie Bowles (3505478)
Alex Côté (6727181)
Rachel Wise (6727184)
Benjamen O’Donnell (6727187)
Margarite Matossian (6040496)
Fokhrul Hossain (6040487)
Hope Burks (6438176)
Luis Valle (6727190)
Lucio Miele (81383)
Bridgette Collins-Burow (444016)
Matthew Burow (3575111)
Bruce Bunnell (3505469)

May 2019

Figure S4. Flow cytometric analysis of PDX tumor shows obASCs promote EMT and increase classically a...

Additional file 7: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Abstract

Extracted data

Additional file 7: of OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Abstract

Extracted data

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