Deletion of miR-146a gene in hematopoietic cells does not increase adhesion in <i>Ldlr</i>^-/- mice fed HFD.

<p>Lethally-irradiated <i>Ldlr</i>^<i>-/-</i> mice (CD45.1, 8 to 10-week-old) were transplanted with cells obtained from bone marrow (BM) of wt or <i>miR-146a</i>^-/- mice (both CD45.2). After 4 weeks of recovery, mice were challenged with a high-fat diet (HFD) for 20 weeks and analyzed by intravital microscopy in the cremaster muscle. Images are representative for Ly6C⁺ monocytes, Ly6G⁺ neutrophils, and CD4⁺ T cells adhered to the wall of cremasteric venules. Dashed lines mark the boundaries of the venules.